The aggregation of amyloid polypeptide plays a crucial role in inducing various chronic
diseases, such as neurodegenerative diseases and type II diabetes. Up to date, amyloid …

The self-association of metabolites into well-ordered assemblies at the nanoscale has
significant biological and medical implications. The thiol-containing amino acid cysteine …

Polymers possessing helical conformation in the solid state are in high demand. We report a
helical peptide-polymer via the topochemical ene-azide cycloaddition (TEAC) …

Antimicrobial activity is being increasingly linked to amyloid fibril formation, suggesting
physiological roles for some human amyloids, which have historically been viewed as strictly …

Biological and synthetic molecular motors, fueled by various physical and chemical means,
can perform asymmetric linear and rotary motions that are inherently related to their …

Protein–protein interactions play a crucial role in microtubule dynamics. Microtubules are
considered as a key target for the design and development of anticancer therapeutics …

Packing a polymer in different ways can give polymorphs of the polymer having different
properties. β-Turn forming peptides such as 2-aminoisobutyric acid (Aib)-rich peptides adopt …

Protein–protein interactions (PPIs) are involved in many of life's essential biological
functions yet are also an underlying cause of several human diseases, including …

Tuning the secondary structure of a protein or polymer in the solidstate is challenging. Here
we report the topochemical synthesis of a pseudoprotein and its secondary structure tuning …

Hierarchical self-assembly based on peptides in nature is a multi-component interaction
process, providing a broad platform for various bionanotechnological applications. However …