Acetylcholinesterase inhibitors in the treatment of neurodegenerative diseases and the role of acetylcholinesterase in their pathogenesis

ŁJ Walczak-Nowicka, M Herbet - International journal of molecular …, 2021 - mdpi.com
Acetylcholinesterase (AChE) plays an important role in the pathogenesis of
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …

Mangiferin: A multipotent natural product preventing neurodegeneration in Alzheimer's and Parkinson's disease models

ST Feng, ZZ Wang, YH Yuan, HM Sun, NH Chen… - Pharmacological …, 2019 - Elsevier
Alzheimer's disease (AD) and Parkinson's disease (PD) are recognized as the universal
neurodegenerative diseases, with the involvement of misfolded proteins pathology, leading …

The role of polyphenols in the modulation of sirtuins and other pathways involved in Alzheimer's disease

T Jayasena, A Poljak, G Smythe, N Braidy… - Ageing research …, 2013 - Elsevier
Alzheimer's disease (AD) is characterised by extracellular amyloid deposits, neurofibrillary
tangles, synaptic loss, inflammation and extensive oxidative stress. Polyphenols, which …

[HTML][HTML] Protective effect of mangiferin on memory impairment: A systematic review

PT Lum, M Sekar, SH Gan, V Pandy… - Saudi journal of biological …, 2021 - Elsevier
Memory impairment (MI) is one of the predominant criteria generally used to identify
schizophrenia, dementia and amnesia that are associated with neurodegenerative disorders …

Protective effect of mangiferin against lipopolysaccharide-induced depressive and anxiety-like behaviour in mice

A Jangra, MM Lukhi, K Sulakhiya, CC Baruah… - European journal of …, 2014 - Elsevier
Numerous studies have demonstrated that inflammation, oxidative stress and altered level of
neurotrophins are involved in the pathogenesis of depressive illness. Mangiferin, a C …

Effects of bioactive molecules on the concentration of biogenic amines in foods and biological systems

PB Tsafack, A Tsopmo - Heliyon, 2022 - cell.com
Biogenic amines (BAs) are a group of molecules naturally present in foods that contain
amino acids, peptides, and proteins as well as in biological systems. In foods, their …

Mangiferin exerts antitumor activity in breast cancer cells by regulating matrix metalloproteinases, epithelial to mesenchymal transition, and β-catenin signaling …

H Li, J Huang, B Yang, T Xiang, X Yin, W Peng… - Toxicology and applied …, 2013 - Elsevier
Although mangiferin which is a naturally occurring glucosylxanthone has exhibited
promising anticancer activities, the detailed molecular mechanism of mangiferin on cancers …

The impact of synthetic and natural additives on biogenic amine production in food products

A Abedini, P Sadighara, MA Sani, DJ McClements - Food Bioscience, 2023 - Elsevier
Biogenic amines (BAs) are compounds that are produced in foods containing proteins and
amino acids by microorganisms. This means that foods that are high in protein, such as …

The role of natural flavonoids on neuroinflammation as a therapeutic target for Alzheimer's disease: a narrative review

Q Zhang, Y Yan - Neural Regeneration Research, 2023 - journals.lww.com
Alzheimer's disease is a neurodegenerative disease that affects a large proportion of older
adult people and is characterized by memory loss, progressive cognitive impairment, and …

Pharmacological properties of mangiferin: Bioavailability, mechanisms of action and clinical perspectives

J Zivković, KA Kumar, R Rushendran, K Ilango… - Naunyn-Schmiedeberg's …, 2024 - Springer
This review aims to provide an in-depth analysis of the pharmacological properties of
mangiferin, focusing primarily on its bioavailability and mechanisms of action, and its …