[HTML][HTML] Use of a MAIT-activating ligand, 5-OP-RU, as a mucosal adjuvant in a murine model of Vibrio cholerae O1 vaccination
Background: Mucosal-associated invariant T (MAIT) cells are innate-like T cells enriched in
the mucosa with capacity for B-cell help. We hypothesize that targeting MAIT cells, using a …
the mucosa with capacity for B-cell help. We hypothesize that targeting MAIT cells, using a …
Identification of Novel MR1 Ligands Derived from Herbal Medicines by MR1-Presentation Reporter Screening and Their Structure-Activity Relationship
T Matsuoka, A Hattori, S Oishi, N Arichi, H Kakeya… - 2022 - chemrxiv.org
Mucosal-associated invariant T (MAIT) cells are innate-like T cells that are modulated by
ligands presented on MHC class I-related proteins (MR1). These cells have attracted …
ligands presented on MHC class I-related proteins (MR1). These cells have attracted …