The aortic valve regulates unidirectional flow of oxygenated blood to the myocardium and
arterial system. The natural anatomical geometry and microstructural complexity ensures …

Valvular heart disease is an increasing population health problem and, especially in the
elderly, a significant cause of morbidity and mortality. The current treatment options, such as …

In this paper we explore the ability of thermal analysis to check elastin and collagen integrity
in different biomaterial applications. Differential Scanning Calorimetry (DSC) has been used …

Tissue-engineered heart valves are proposed as novel viable replacements granting longer
durability and growth potential. However, they require extensive in vitro cell-conditioning in …

Decellularization, sterilization, and hemocompatibility are the main areas for biomaterials
evaluation when the material is designed for medical implants. The glutaraldehyde fixation …

This study features the longest experimental follow‐up for decellularized heart valves
implanted in an animal model. Porcine aortic heart valves were decellularized according to …

In the development of tissue-engineered heart valves based on allograft decellularized
extracellular matrix scaffolds, the material properties of the implant should be ideally …

Decellularized porcine aortic valve conduits (AVCs) implanted in a Vietnamese Pig (VP)
experimental animal model were matched against decellularized and then cryopreserved …

Glutaraldehyde-treated, surgical bioprosthetic heart valves undergo structural degeneration
within 10–15 years of implantation. Analogous preliminary results were disclosed for …

This work is devoted to the characterization of type I collagen treated by a low-temperature
plasma jet generated in ambient air to determine whether the resulting fibrous material is …