Identification of COX-2 inhibitors via structure-based virtual screening and molecular dynamics simulation

N Razzaghi-Asl, S Mirzayi, K Mahnam… - Journal of Molecular …, 2018 - Elsevier
In an attempt to identify potential COX-2 inhibitors, a multi-step virtual screening strategy
was performed on a series of compounds. For this purpose, ZINC database was screened …

Alpha glucosidase inhibitory properties of a few bioactive compounds isolated from black rice bran: combined in vitro and in silico evidence supporting the antidiabetic …

P Bhuyan, M Ganguly, I Baruah, G Borgohain… - RSC …, 2022 - pubs.rsc.org
In view of the recent reports of the antidiabetic effect of the black rice bran extract, an attempt
has been made in the present work to evaluate the potential α-glucosidase inhibitory activity …

[HTML][HTML] An in vitro and in silico antidiabetic approach of GC–MS detected friedelin of Bridelia retusa

S Kumar, D Kumar, M Sahu, NS Maurya, A Mani… - Journal of King Saud …, 2024 - Elsevier
Bridelia retusa is a medicinal plant widely used to treat diabetes by ethnic populations
worldwide, has been subjected to GC–MS-based profiling for the bark and fruit and …

Potensi Fitokimia Citrus Aurantium (Hesperetin, Naringenin) Dalam Menghambat Xantin Okisidase Pada Hiperurisemia Secara In Silico

M Fakhruri, Y Rahmayanti - Jurnal Health Sains, 2021 - jurnal.healthsains.co.id
Prevalsensi penderita hiperusemia cenderung meningkat dalam beberapa dekade. Obat
golongan xantin oksidase inhibitor digunakan untuk hiperurisemia. Citrus aurantium …

[PDF][PDF] In silico screening of cinnamon (Cinnamomum burmannii) bioactive compounds as acetylcholinesterase inhibitors

ZYI Syarafina, M Safithri, M Bintang… - Jurnal Kimia Sains Dan …, 2022 - researchgate.net
Alzheimer's is a progressive and neurodegenerative disease that mainly affects people
aged 65 years and older. The pathophysiology of Alzheimer's is possibly related to the …

[PDF][PDF] Penapisan virtual senyawa aktif sirih merah (Piper crocatum) sebagai inhibitor angiotensin converting enzyme

RAP Irsal, DSH Seno, M Safithri… - Jurnal Farmamedika …, 2022 - academia.edu
Lisinopril merupakan obat inhibitor Angiotensin Converting Enzyme yang menjadi pilihan
utama dalam pengobatan hipertensi, namun obat ini memiliki efek samping. Sirih merah …

[PDF][PDF] Molecular docking of red betel (Piper crocatum Ruiz & Pav) bioactive compounds as HMG-CoA reductase inhibitor

BFD Zaelani, M Safithri, D Andrianto - Jurnal Kimia Sains Dan …, 2021 - academia.edu
Cholesterol plaque buildup in artery walls occurs due to oxidation of Low-Density
Lipoprotein (LDL) molecules by free radicals, which are a risk factor for coronary heart …

[PDF][PDF] Penambatan Molekuler Senyawa Aktif Sirih Merah (Piper crocatum) pada Butirilkolinesterase sebagai Kandidat Antialzheimer

RG Putri, M Safithri, H Husnawati… - … Jurnal Penelitian Kimia, 2023 - academia.edu
Alzheimer adalah salah satu penyakit neurodegeneratif kronis dan menjadi penyakit yang
sering dialami oleh orang lanjut usia. Perubahan yang terjadi dari penyakit Alzheimer, yakni …

In Silico Analysis of Bioactive Compounds in Red Betel Leaves to Glutathion Peroxidase Activity

MA Umar, M Safithri, R Pratama - Indonesian Journal of Applied …, 2022 - iojs.unida.ac.id
Glutathione peroxidase (GPx) is one of the antioxidants that acts as a protector of organisms
from oxidative stress. Several compounds in certain plants have been shown to increase …

Bioavailability and molecular recognition between secondary metabolites of Euphorbia hirta L. and 5-lipoxygenase using fragment molecular orbital method and pair …

E Marcano, Y Sánchez - Revista de la Facultad de Farmacia, 2024 - saber.ucv.ve
Is presented the bioavailability analysis for seven secondary metabolites from Euphorbia
hirta L.(Euphorbiaceae). The bioactivity score, the molecular similarity analysis for each …