Malaria: biology and disease
Malaria has been a major global health problem of humans through history and is a leading
cause of death and disease across many tropical and subtropical countries. Over the last …
cause of death and disease across many tropical and subtropical countries. Over the last …
Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria
Malaria accounts for an enormous burden of disease globally, with Plasmodium falciparum
accounting for the majority of malaria, and P. vivax being a second important cause …
accounting for the majority of malaria, and P. vivax being a second important cause …
[HTML][HTML] Malaria diagnosis: a brief review
N Tangpukdee, C Duangdee… - The Korean journal of …, 2009 - ncbi.nlm.nih.gov
Malaria is a major cause of death in tropical and sub-tropical countries, killing each year
over 1 million people globally; 90% of fatalities occur in African children. Although effective …
over 1 million people globally; 90% of fatalities occur in African children. Although effective …
Reverse vaccinology: developing vaccines in the era of genomics
A Sette, R Rappuoli - Immunity, 2010 - cell.com
The sequence of microbial genomes made all potential antigens of each pathogen available
for vaccine development. This increased by orders of magnitude potential vaccine targets in …
for vaccine development. This increased by orders of magnitude potential vaccine targets in …
A prospective analysis of the Ab response to Plasmodium falciparum before and after a malaria season by protein microarray
PD Crompton, MA Kayala, B Traore… - Proceedings of the …, 2010 - National Acad Sciences
Abs are central to malaria immunity, which is only acquired after years of exposure to
Plasmodium falciparum (Pf). Despite the enormous worldwide burden of malaria, the targets …
Plasmodium falciparum (Pf). Despite the enormous worldwide burden of malaria, the targets …
Novel serologic biomarkers provide accurate estimates of recent Plasmodium falciparum exposure for individuals and communities
Tools to reliably measure Plasmodium falciparum (Pf) exposure in individuals and
communities are needed to guide and evaluate malaria control interventions. Serologic …
communities are needed to guide and evaluate malaria control interventions. Serologic …
Advances and challenges in malaria vaccine development
PD Crompton, SK Pierce… - The Journal of clinical …, 2010 - Am Soc Clin Investig
Malaria caused by Plasmodium falciparum remains a major public health threat, especially
among children and pregnant women in Africa. An effective malaria vaccine would be a …
among children and pregnant women in Africa. An effective malaria vaccine would be a …
Overview of protein microarrays
FXR Sutandy, J Qian, CS Chen… - Current protocols in …, 2013 - Wiley Online Library
Protein microarray technology is an emerging field that provides a versatile platform for the
characterization of hundreds of thousands of proteins in a highly parallel and high …
characterization of hundreds of thousands of proteins in a highly parallel and high …
New antigens for a multicomponent blood-stage malaria vaccine
An effective blood-stage vaccine against Plasmodium falciparum remains a research
priority, but the number of antigens that have been translated into multicomponent vaccines …
priority, but the number of antigens that have been translated into multicomponent vaccines …
Genetic diversity and malaria vaccine design, testing and efficacy: preventing and overcoming 'vaccine resistant malaria'
SL Takala, CV Plowe - Parasite immunology, 2009 - Wiley Online Library
The development of effective malaria vaccines may be hindered by extensive genetic
diversity in the surface proteins being employed as vaccine antigens. Understanding of the …
diversity in the surface proteins being employed as vaccine antigens. Understanding of the …