Studies of bacterial and eukaryotic systems have identified two-gene operons in which the
translation product of the upstream gene influences translation of the downstream gene. The …

A minimally addressed area in Saccharomyces cerevisiae research is the mapping of
transcription start sites (TSS). Mapping of TSS in S. cerevisiae has the potential to contribute …

The Srb mediator is an important transcriptional coactivator for Gcn4p in the yeast
Saccharomyces cerevisiae. We show that three subunits of the Gal11/tail domain of …

The interaction of Candida albicans with phagocytes of the host's innate immune system is
highly dynamic, and its outcome directly impacts the progression of infection. While the …

Regulated protein destruction by the proteasome is crucial for the maintenance of normal
cellular homeostasis. Much of our understanding of proteasome function stems from the use …

The expression of inulinolytic genes in Aspergillus niger is co-regulated and induced by
inulin and sucrose. We have identified a positive acting transcription factor InuR, which is …

The Neurospora crassa arg-2 transcript contains an upstream open reading frame (uORF)
specifying a 24-residue leader peptide and is subject to a novel form of negative …

Transcriptional regulation of the Saccharomyces cerevisiae ARG1 gene is controlled by
positive and negative elements. The transactivator Gcn4p is required for activation in …

Transcription of the Saccharomyces cerevisiae ARG1 gene is under the control of both
positive and negative elements. Activation of the gene in minimal medium is induced by …

Perhaps one of the most delightful characteristics of biology is that just when we think we
know all about something, a new observation comes along that exposes our state of …