UFMylation: a ubiquitin-like modification
X Zhou, SJ Mahdizadeh, M Le Gallo… - Trends in Biochemical …, 2024 - cell.com
Post-translational modifications (PTMs) add a major degree of complexity to the proteome
and are essential controllers of protein homeostasis. Amongst the hundreds of PTMs …
and are essential controllers of protein homeostasis. Amongst the hundreds of PTMs …
A guide to UFMylation, an emerging posttranslational modification
Ubiquitin Fold Modifier‐1 (UFM1) is a ubiquitin‐like modifier (UBL) that is posttranslationally
attached to lysine residues on substrates via a dedicated system of enzymes conserved in …
attached to lysine residues on substrates via a dedicated system of enzymes conserved in …
[HTML][HTML] UBA5 inhibition restricts lung adenocarcinoma via blocking macrophage M2 polarization and cisplatin resistance
D Xu, D Zhang, W Wei, C Zhang - Experimental Cell Research, 2024 - Elsevier
UBA5, a ubiquitin-like activated enzyme involved in ufmylation and sumoylation, presents a
viable target for pancreatic and breast cancer treatments, yet its role in lung …
viable target for pancreatic and breast cancer treatments, yet its role in lung …
[PDF][PDF] Mithramycin targets head and neck cancer stem cells by inhibiting Sp1 and UFMylation
KV Derfi, T Vasiljevic, T Dragicevic, TM Glavan - Cancer cell international, 2024 - Springer
Background The development of resistance to therapy is characteristic of head and neck
squamous cell carcinoma (HNSCC), the 6th most common cancer, and is often attributed to …
squamous cell carcinoma (HNSCC), the 6th most common cancer, and is often attributed to …
[HTML][HTML] Patient derived model of UBA5-associated encephalopathy identifies defects in neurodevelopment and highlights potential therapies
H Chen, YD Wang, AW Blan, EP Almanza-Fuerte… - bioRxiv, 2024 - ncbi.nlm.nih.gov
UBA5 encodes for the E1 enzyme of the UFMylation cascade, which plays an essential role
in ER homeostasis. The clinical phenotypes of UBA5-associated encephalopathy include …
in ER homeostasis. The clinical phenotypes of UBA5-associated encephalopathy include …
Understanding the role UFMylation plays in prostate cancer
DS Gill - 2024 - eprints.qut.edu.au
The aim of this research was to identify proteins that are modified by a post-translational
process called UFMylation in prostate cancer. Despite being discovered two decades ago …
process called UFMylation in prostate cancer. Despite being discovered two decades ago …