A comprehensive review of monoamine oxidase inhibitors as Anti-Alzheimer's disease agents: A review

S Manzoor, N Hoda - European journal of medicinal chemistry, 2020 - Elsevier
Monoamine oxidases (MAO-A and MAO-B) are mammalian flavoenzyme, which catalyze the
oxidative deamination of several neurotransmitters like norepinephrine, dopamine, tyramine …

[HTML][HTML] The human flavoproteome

WD Lienhart, V Gudipati, P Macheroux - Archives of biochemistry and …, 2013 - Elsevier
Vitamin B2 (riboflavin) is an essential dietary compound used for the enzymatic biosynthesis
of FMN and FAD. The human genome contains 90 genes encoding for flavin-dependent …

[图书][B] Amino acid metabolism

DA Bender - 2012 - books.google.com
Amino Acid Metabolism, 3rd Edition covers all aspects of the biochemistry and nutritional
biochemistry of the amino acids. Starting with an overview of nitrogen fixation and the …

A systematic review of histone lysine‐specific demethylase 1 and its inhibitors

YC Zheng, J Ma, Z Wang, J Li, B Jiang… - Medicinal research …, 2015 - Wiley Online Library
Histone lysine‐specific demethylase 1 (LSD1) is the first discovered and reported histone
demethylase by Dr. Shi Yang's group in 2004. It is classified as a member of amine oxidase …

Structures and mechanism of the monoamine oxidase family

H Gaweska, PF Fitzpatrick - 2011 - degruyter.com
Members of the monoamine oxidase family of flavoproteins catalyze the oxidation of primary
and secondary amines, polyamines, amino acids, and methylated lysine side chains in …

The redox basis of epigenetic modifications: from mechanisms to functional consequences

AR Cyr, FE Domann - Antioxidants & redox signaling, 2011 - liebertpub.com
Epigenetic modifications represent mechanisms by which cells may effectively translate
multiple signaling inputs into phenotypic outputs. Recent research is revealing that redox …

Pharmacological inhibition of LSD1 for cancer treatment

GJ Yang, PM Lei, SY Wong, DL Ma, CH Leung - Molecules, 2018 - mdpi.com
Lysine-specific demethylase 1A (LSD1, also named KDM1A) is a demethylase that can
remove methyl groups from histones H3K4me1/2 and H3K9me1/2. It is aberrantly expressed …

Formaldehyde in brain: an overlooked player in neurodegeneration?

K Tulpule, R Dringen - Journal of Neurochemistry, 2013 - Wiley Online Library
Formaldehyde is an environmental pollutant that is also generated in substantial amounts in
the human body during normal metabolism. This aldehyde is a well‐established neurotoxin …

Epigenetics in ovarian cancer: premise, properties, and perspectives

Q Yang, Y Yang, N Zhou, K Tang, WB Lau, B Lau… - Molecular cancer, 2018 - Springer
Malignant ovarian tumors bear the highest mortality rate among all gynecological cancers.
Both late tumor diagnosis and tolerance to available chemical therapy increase patient …

Coordinated chromatin control: structural and functional linkage of DNA and histone methylation

X Cheng, RM Blumenthal - Biochemistry, 2010 - ACS Publications
One of the most fundamental questions in the control of gene expression in mammals is how
epigenetic methylation patterns of DNA and histones are established, erased, and …