[HTML][HTML] Chronic effects of air pollution on respiratory health in Southern California children: findings from the Southern California Children's Health Study

Z Chen, MT Salam, SP Eckel, CV Breton… - Journal of thoracic …, 2015 - ncbi.nlm.nih.gov
Outdoor air pollution is one of the leading contributors to adverse respiratory health
outcomes in urban areas around the world. Children are highly sensitive to the adverse …

Air pollution, epigenetics, and asthma

H Ji, JM Biagini Myers, EB Brandt, C Brokamp… - Allergy, Asthma & …, 2016 - Springer
Exposure to traffic-related air pollution (TRAP) has been implicated in asthma development,
persistence, and exacerbation. This exposure is highly significant as large segments of the …

Exhaled nitric oxide levels and blood eosinophil counts independently associate with wheeze and asthma events in National Health and Nutrition Examination Survey …

A Malinovschi, JA Fonseca, T Jacinto, K Alving… - Journal of allergy and …, 2013 - Elsevier
Background Fraction of exhaled nitric oxide (F eno) and blood eosinophil count (B-Eos)
values, markers of local and systemic eosinophilic inflammation, respectively, are increased …

Genetic and epigenetic variations in inducible nitric oxide synthase promoter, particulate pollution, and exhaled nitric oxide levels in children

MT Salam, HM Byun, F Lurmann, CV Breton… - Journal of Allergy and …, 2012 - Elsevier
BACKGROUND: Inducible nitric oxide synthase (iNOS; encoded by nitric oxide synthase
isoform 2 [NOS2]) is the major enzyme for nitric oxide synthesis in airways. As such …

The effect of ambient air pollution on exhaled nitric oxide in the Children's Health Study

K Berhane, Y Zhang, WS Linn… - European …, 2011 - Eur Respiratory Soc
We assessed the effect of daily variations in ambient air pollutants on exhaled nitric oxide
fraction (F eNO) using data from a cohort of school children with large differences in air …

Maternal second-hand smoke exposure in pregnancy is associated with childhood asthma development

E Simons, T To, R Moineddin, D Stieb… - The Journal of Allergy and …, 2014 - Elsevier
Background Childhood asthma development has been associated with active maternal
smoking during pregnancy, but its association with maternal second-hand smoke exposure …

Particulate matter, DNA methylation in nitric oxide synthase, and childhood respiratory disease

CV Breton, MT Salam, X Wang, HM Byun… - Environmental …, 2012 - ehp.niehs.nih.gov
Background: Air pollutants have been associated with childhood asthma and wheeze.
Epigenetic regulation of nitric oxide synthase—the gene responsible for nitric oxide …

DNA methylation in the arginase–nitric oxide synthase pathway is associated with exhaled nitric oxide in children with asthma

CV Breton, HM Byun, X Wang, MT Salam… - American journal of …, 2011 - atsjournals.org
Rationale: Genetic variation in arginase (ARG) and nitric oxide synthase (NOS) has been
associated with exhaled nitric oxide (FeNO) levels in children. Little is known about whether …

Susceptibility of individuals with chronic obstructive pulmonary disease to respiratory inflammation associated with short-term exposure to ambient air pollution: A …

Y Yao, X Chen, W Chen, Q Wang, Y Fan, Y Han… - Science of The Total …, 2021 - Elsevier
Background Chronic obstructive pulmonary disease (COPD) is a leading cause of death
worldwide. There is no clear evidence of whether COPD patients are more susceptible to …

Exhaled NO: determinants and clinical application in children with allergic airway disease

HB Kim, SP Eckel, JH Kim… - Allergy, Asthma & …, 2016 - synapse.koreamed.org
Nitric oxide (NO) is endogenously released in the airways, and the fractional concentration
of NO in exhaled breath (FeNO) is now recognized as a surrogate marker of eosinophilic …