Towards understanding the function of aegerolysins

N Kraševec, M Skočaj - Toxins, 2022 - mdpi.com
Aegerolysins are remarkable proteins. They are distributed over the tree of life, being
relatively widespread in bacteria and fungi, but also present in some insects, plants …

What can mushroom proteins teach us about lipid rafts?

M Grundner, A Panevska, K Sepčić, M Skočaj - Membranes, 2021 - mdpi.com
The lipid raft hypothesis emerged as a need to explain the lateral organization and behavior
of lipids in the environment of biological membranes. The idea, that lipids segregate in …

Characterization and cytotoxic activity of ribotoxin-like proteins from the edible mushroom Pleurotus eryngii

N Landi, M Grundner, S Ragucci, M Pavšič, M Mravinec… - Food Chemistry, 2022 - Elsevier
Ribotoxin-like proteins (RL-Ps) represent a novel specific ribonuclease family found in
edible mushrooms and are able to inhibit protein synthesis. Here, we report the …

Dissecting out the molecular mechanism of insecticidal activity of ostreolysin A6/pleurotolysin B complexes on western corn rootworm

M Milijaš Jotić, A Panevska, I Iacovache, R Kostanjšek… - Toxins, 2021 - mdpi.com
Ostreolysin A6 (OlyA6) is a protein produced by the oyster mushroom (Pleurotus ostreatus).
It binds to membrane sphingomyelin/cholesterol domains, and together with its protein …

Protein complexes from edible mushrooms as a sustainable potato protection against coleopteran pests

K Pogačar, M Grundner, P Žigon, A Coll… - Plant Biotechnology …, 2024 - Wiley Online Library
Protein complexes from edible oyster mushrooms (Pleurotus sp.) composed of pleurotolysin
A2 (PlyA2) and pleurotolysin B (PlyB) exert toxicity in feeding tests against Colorado potato …

Ceramide aminoethylphosphonate as a new molecular target for pore-forming aegerolysin-based protein complexes

T Balbi, F Trenti, A Panevska, G Bajc… - Frontiers in Molecular …, 2022 - frontiersin.org
Ostreolysin A6 (OlyA6) is a 15 kDa protein produced by the oyster mushroom (Pleurotus
ostreatus). It belongs to the aegerolysin family of proteins and binds with high affinity to the …

Suitability of maize crop residue fermented by Pleurotus ostreatus as feed for edible crickets: growth performance, micronutrient content, and iron bioavailability

M Ventura, ME Holland, MB Smith, JM Chaparro… - Frontiers in …, 2023 - frontiersin.org
Small-scale farming of edible insects could help combat public health challenges such as
protein energy malnutrition and anemia, but reliable low-cost feeds for insects are needed …

Ceramide phosphoethanolamine as a possible marker of periodontal disease

M Grundner, H Munjaković, T Tori, K Sepčić… - Membranes, 2022 - mdpi.com
Periodontal disease is a chronic oral inflammatory disorder initiated by pathobiontic bacteria
found in dental plaques—complex biofilms on the tooth surface. The disease begins as an …

A single point mutation expands the applicability of ostreolysin A6 in biomedicine

A Panevska, N Čegovnik, K Fortuna, A Vukovič… - Scientific Reports, 2023 - nature.com
An aegerolysin protein ostreolysin A6 (OlyA6) binds to cholesterol-complexed
sphingomyelin and can be used for specific labelling of lipid rafts. In addition, OlyA6 …

Lessons on fruiting body morphogenesis from genomes and transcriptomes of Agaricomycetes

LG Nagy, PJ Vonk, M Künzler, C Földi… - Studies in …, 2023 - ingentaconnect.com
Fruiting bodies (sporocarps, sporophores or basidiomata) of mushroom-forming fungi
(Agaricomycetes) are among the most complex structures produced by fungi. Unlike …