Research elucidating the pathogenesis of systemic lupus erythematosus (SLE) has defined
two critical families of mediators, type I interferon (IFN-I) and autoantibodies targeting nucleic …

Impressive progress has been made over the last several years toward understanding how
almost every aspect of the immune system contributes to the expression of systemic …

The use of vaccines have resulted in a remarkable improvement in global health. It has
saved several lives, reduced treatment costs and raised the quality of animal and human …

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of complex etiology
that primarily affects women of childbearing age. The development of SLE is attributed to the …

Systemic lupus erythematosus, systemic sclerosis, rheumatoid arthritis, and Sjögren's
syndrome are four major autoimmune rheumatic diseases characterized by the presence of …

There is growing evidence that preceding the diagnosis or classification of systemic lupus
erythematosus (SLE), patients undergo a preclinical phase of disease where markers of …

Systemic lupus erythematosus (SLE) is a polygenic chronic autoimmune disease leading to
multiple organ damage. A large heritability of up to 66% is estimated in SLE, with roughly …

B cells expressing the transcription factor T-bet are found to have a protective role in viral
infections, but are also considered major players in the onset of different types of …

Systemic Lupus Erythematosus (SLE) is a systemic autoimmune disease that attacks various
organ systems with a variety of clinical implications, ranging from mild skin and mucosal …

Abstract The analysis of Adverse Events Following Immunization (AEFI) is important in a
balanced epidemiological evaluation of vaccines and in the issues related to vaccine injury …