Bioactive peptides and proteins from centipede venoms
Y Han, PM Kamau, R Lai, L Luo - Molecules, 2022 - mdpi.com
Venoms are a complex cocktail of biologically active molecules, including peptides, proteins,
polyamide, and enzymes widely produced by venomous organisms. Through long-term …
polyamide, and enzymes widely produced by venomous organisms. Through long-term …
Molecular evolution of gland cell types and chemical interactions in animals
A Brückner, J Parker - Journal of Experimental Biology, 2020 - journals.biologists.com
Across the Metazoa, the emergence of new ecological interactions has been enabled by the
repeated evolution of exocrine glands. Specialized glands have arisen recurrently and with …
repeated evolution of exocrine glands. Specialized glands have arisen recurrently and with …
Genome of the pincer wasp Gonatopus flavifemur reveals unique venom evolution and a dual adaptation to parasitism and predation
Background Hymenoptera comprise extremely diverse insect species with extensive
variation in their life histories. The Dryinidae, a family of solitary wasps of Hymenoptera …
variation in their life histories. The Dryinidae, a family of solitary wasps of Hymenoptera …
Phylogenetic analyses suggest centipede venom arsenals were repeatedly stocked by horizontal gene transfer
EAB Undheim, RA Jenner - Nature Communications, 2021 - nature.com
Venoms have evolved over a hundred times in animals. Venom toxins are thought to evolve
mostly by recruitment of endogenous proteins with physiological functions. Here we report …
mostly by recruitment of endogenous proteins with physiological functions. Here we report …
Utilisation of compounds from venoms in drug discovery
Difficult drug targets are becoming the normal course of business in drug discovery,
sometimes due to large interacting surfaces or only small differences in selectivity regions …
sometimes due to large interacting surfaces or only small differences in selectivity regions …
Duvernoy's Gland Transcriptomics of the Plains Black-Headed Snake, Tantilla nigriceps (Squamata, Colubridae): Unearthing the Venom of Small Rear-Fanged …
The venoms of small rear-fanged snakes (RFS) remain largely unexplored, despite
increased recognition of their importance in understanding venom evolution more broadly …
increased recognition of their importance in understanding venom evolution more broadly …
The arylsulfatase-and phospholipase-rich venom of the plutoniumid centipede Theatops posticus
AN Lane, PD Nash, SA Ellsworth, GS Nystrom… - Toxicon, 2023 - Elsevier
Research on centipede venoms has led to the discovery of a diverse array of novel proteins
and peptides, including those with homology to previously discovered toxin families (eg …
and peptides, including those with homology to previously discovered toxin families (eg …
Selection Across the Three-Dimensional Structure of Venom Proteins from North American Scolopendromorph Centipedes
SA Ellsworth, RM Rautsaw, MJ Ward… - Journal of Molecular …, 2024 - Springer
Gene duplication followed by nucleotide differentiation is one of the simplest mechanisms to
develop new functions for genes. However, the evolutionary processes underlying the …
develop new functions for genes. However, the evolutionary processes underlying the …
Anatomical constraints on venom and toxin evolution in centipedes
S Hverven - 2022 - duo.uio.no
Centipedes are among the oldest groups of venomous predatory arthropods. They have had
similar morphology and life history for many million years and can be compared with …
similar morphology and life history for many million years and can be compared with …