Aim A systemic review and analysis of evolution journey of indices, such as conformity index
(CI), homogeneity index (HI) and gradient index (GI), described in the literature. Background …

Recently, deep learning has accomplished the automation of radiation therapy planning,
enhancing its quality and efficiency. However, such progress comes at the cost of a large …

The aim of this study was to estimate the radiation-related secondary cancer risks in organs
during the treatment of breast cancer with different radiotherapy techniques, such as three …

Background and purpose Low-grade glioma (LGG) is a very common brain tumor in
pediatric patients typically associated with a very good prognosis. This prognosis makes it …

Purpose This study evaluated whether RapidPlan based plans (RP plans) created by a
single optimization, are usable in volumetric modulated arc therapy (VMAT) for patients with …

Background. Radiotherapy (RT) plays a fundamental role in the treatment of pediatric central
nervous system (CNS) malignancies, but its late sequelae are still a challenging question …

Abstract Purpose Conventional techniques (3D-CRT) for craniospinal irradiation (CSI) are
still widely used. Modern techniques (IMRT, VMAT, TomoTherapy®, proton pencil beam …

Purpose It has been known for over 100 years that tumor hypoxia, a near-universal
characteristic of solid tumors, decreases the curative effectiveness of radiation therapy …

Background Adjuvant radiotherapy is the standard treatment after breast-conserving
surgery. According to meta-analyses, adjuvant 3d-conventional irradiation reduces the risk …

Purpose The aim of this study was to evaluate the performance of very high‐energy electron
beams (VHEE) in comparison to clinically derived treatment plans generated with volumetric …