[HTML][HTML] Keratoconus: An updated review

J Santodomingo-Rubido, G Carracedo, A Suzaki… - Contact Lens and …, 2022 - Elsevier
Keratoconus is a bilateral and asymmetric disease which results in progressive thinning and
steeping of the cornea leading to irregular astigmatism and decreased visual acuity …

The keratoconus enigma: a review with emphasis on pathogenesis

G Ferrari, P Rama - The Ocular Surface, 2020 - Elsevier
Purpose To review the literature on the etiopathogenesis of keratoconus (KC). Methods A
literature search was conducted using PUBMED and Google Scholar for keratoconus. The …

Biomechanics and structure of the cornea: implications and association with corneal disorders

J Ma, Y Wang, P Wei, V Jhanji - Survey of ophthalmology, 2018 - Elsevier
Recent studies have shown that alterations in corneal biomechanical properties are
associated with corneal pathologies, particularly corneal ectasia. Moreover, these …

[HTML][HTML] Molecular and histopathological changes associated with keratoconus

ML Khaled, I Helwa, M Drewry, M Seremwe… - BioMed research …, 2017 - hindawi.com
Keratoconus (KC) is a corneal thinning disorder that leads to loss of visual acuity through
ectasia, opacity, and irregular astigmatism. It is one of the leading indicators for corneal …

Cornea and sclera: anatomy and physiology

T Nishida, S Saika, N Morishige - Cornea, 2021 - books.google.com
Collagen fibrils are homogeneous in diameter and are aligned at a constant distance from
each other to maintain tissue transparency. Keratocytes are the resident cells of the stroma …

[HTML][HTML] Comparisons of corneal biomechanical and tomographic parameters among thin normal cornea, forme fruste keratoconus, and mild keratoconus

L Tian, D Zhang, L Guo, X Qin, H Zhang, H Zhang… - Eye and vision, 2021 - Springer
Background To compare the dynamic corneal response (DCR) and tomographic parameters
of thin normal cornea (TNC) with thinnest corneal thickness (TCT)(≤ 500 µm), forme fruste …

[HTML][HTML] Elastic microfibril distribution in the cornea: Differences between normal and keratoconic stroma

TL White, PN Lewis, RD Young, K Kitazawa… - Experimental eye …, 2017 - Elsevier
The optical and biomechanical properties of the cornea are largely governed by the
collagen-rich stroma, a layer that represents approximately 90% of the total thickness. Within …

[HTML][HTML] Characterization of non-linear mechanical behavior of the cornea

A Ashofteh Yazdi, J Melchor, J Torres, I Faris… - Scientific reports, 2020 - nature.com
The objective of this study was to evaluate which hyperelastic model could best describe the
non-linear mechanical behavior of the cornea, in order to characterize the capability of the …

[HTML][HTML] In vivo two-photon microscopy of the human eye

FJ Ávila, A Gambín, P Artal, JM Bueno - Scientific reports, 2019 - nature.com
Abstract Two-photon (2P) microscopy is a powerful tool for imaging and exploring label-free
biological tissues at high resolution. Although this type of microscopy has been …

Three‐dimensional mapping of the orientation of collagen corneal lamellae in healthy and keratoconic human corneas using SHG microscopy

R Mercatelli, F Ratto, F Rossi, F Tatini… - Journal of …, 2017 - Wiley Online Library
Keratoconus is an eye disorder that causes the cornea to take an abnormal conical shape,
thus impairing its refractive functions and causing blindness. The late diagnosis of …