[HTML][HTML] Regenerative potential of mesenchymal stem cells'(MSCs) secretome for liver fibrosis therapies

SR Nazarie, S Gharbia, A Hermenean… - International Journal of …, 2021 - mdpi.com
Chronic liver injuries lead to liver fibrosis and then to end-stage liver cirrhosis. Liver
transplantation is often needed as a course of treatment for patients in critical conditions, but …

[HTML][HTML] Transforming growth factor‑β family and stem cell‑derived exosome therapeutic treatment in osteoarthritis

KH Yoo, N Thapa, YJ Chwae… - International …, 2022 - spandidos-publications.com
Osteoarthritis (OA), although extensively researched, still lacks an effective and safe
treatment. The only current treatment option available for advanced OA is joint replacement …

3D collagen microfibers stimulate the functionality of preadipocytes and maintain the phenotype of mature adipocytes for long term cultures

F Louis, S Kitano, JF Mano, M Matsusaki - Acta biomaterialia, 2019 - Elsevier
Although adipose tissue is one of the most abundant tissues of the human body, its
reconstruction remains a competitive challenge. The conventional in vitro two or three …

[HTML][HTML] Versatile biomaterial platform enriched with graphene oxide and carbon nanotubes for multiple tissue engineering applications

SR Ignat, AD Lazăr, A Şelaru, I Samoilă… - International journal of …, 2019 - mdpi.com
Carbon-based nanomaterials, such as graphene oxide (GO) or carbon nanotubes (CNTs)
are currently used in various medical applications due to their positive influence on …

Collagen substrate stiffness anisotropy affects cellular elongation, nuclear shape, and stem cell fate toward anisotropic tissue lineage

A Islam, M Younesi, T Mbimba… - Advanced healthcare …, 2016 - Wiley Online Library
Rigidity of substrates plays an important role in stem cell fate. Studies are commonly carried
out on isotropically stiff substrate or substrates with unidirectional stiffness gradients …

Focal adhesion kinase and ROCK signaling are switch‐like regulators of human adipose stem cell differentiation towards osteogenic and adipogenic lineages

L Hyväri, M Ojansivu, M Juntunen… - Stem cells …, 2018 - Wiley Online Library
Adipose tissue is an attractive stem cell source for soft and bone tissue engineering
applications and stem cell therapies. The adipose‐derived stromal/stem cells (ASCs) have a …

Biocompatibility Assessment of Novel Collagen‐Sericin Scaffolds Improved with Hyaluronic Acid and Chondroitin Sulfate for Cartilage Regeneration

S Dinescu, B Gălăţeanu, M Albu… - BioMed research …, 2013 - Wiley Online Library
Cartilage tissue engineering (CTE) applications are focused towards the use of implantable
biohybrids consisting of biodegradable scaffolds combined with in vitro cultured cells …

Preparation of a soft and interconnected macroporous hydroxypropyl cellulose methacrylate scaffold for adipose tissue engineering

SP Hoo, QL Loh, Z Yue, J Fu, TTY Tan… - Journal of Materials …, 2013 - pubs.rsc.org
This study describes the preparation and characterization of a biodegradable 3D hydrogel
constructed from hydroxypropyl cellulose (HPC), modified with bifunctional methacrylic …

[HTML][HTML] Fabrication and biocompatibility evaluation of nanodiamonds-gelatin electrospun materials designed for prospective tissue regeneration applications

A Şelaru, DM Drăgușin, E Olăreț, A Serafim… - Materials, 2019 - mdpi.com
Due to the reduced ability of most harmed tissues to self-regenerate, new strategies are
being developed in order to promote self-repair assisted or not by biomaterials, among …

In Vitro Studies of Bacterial Cellulose and Magnetic Nanoparticles Smart Nanocomposites for Efficient Chronic Wounds Healing

B Galateanu, MC Bunea, P Stanescu… - Stem cells …, 2015 - Wiley Online Library
The quality of life of patients with chronic wounds can be extremely poor and, therefore, over
the past decades, great efforts have been made to develop efficient strategies to improve the …