In this narrative review, a theoretical framework on the crosstalk between physical exercise
and blood-brain barrier (BBB) permeability is presented. We discuss the influence of …

Background Wearable sensor technologies have the potential to improve monitoring in
people with multiple sclerosis (MS) and inform timely disease management decisions …

Objectives: To provide clinicians who treat multiple sclerosis (MS) patients with evidence-
based or expert opinion–based recommendations for promoting exercise and lifestyle …

Background Changes in physical activity (PA) are difficult to interpret because no framework
of minimal important difference (MID) exists. We aimed to determine the minimal important …

Objective To perform a systematic review of studies using remote physical activity monitoring
in neurological diseases, highlighting advances and determining gaps. Methods Studies …

The Canadian Multiple Sclerosis Working Group has updated its treatment optimization
recommendations (TORs) on the optimal use of disease-modifying therapies for patients …

Background There has been remarkable growth in research examining physical activity
behavior (any bodily movement produced by skeletal muscle contraction that results in …

Background Declining physical activity commonly occurs in people with Parkinson disease
(PD) and contributes to reduced functional capacity and quality of life. Objective The …

Disability measures in multiple sclerosis (MS) rely heavily on ambulatory function, and
current metrics fail to capture potentially important variability in walking behavior. We sought …

Importance Disability measures in multiple sclerosis (MS) fail to capture potentially important
variability in walking behavior. More sensitive and ecologically valid outcome measures are …