[HTML][HTML] Biological and clinical aspects of metastatic spinal tumors

J Litak, W Czyżewski, M Szymoniuk, L Sakwa… - Cancers, 2022 - mdpi.com
Simple Summary Spine metastases are a common life-threatening complication of
advanced-stage malignancies and often result in poor prognosis. Symptomatic spine …

[HTML][HTML] The bone marrow microenvironment mechanisms in acute myeloid leukemia

DB Pimenta, VA Varela, TS Datoguia… - Frontiers in Cell and …, 2021 - frontiersin.org
Bone marrow (BM) is a highly complex tissue that provides important regulatory signals to
orchestrate hematopoiesis. Resident and transient cells occupy and interact with some well …

[HTML][HTML] Mesenchymal stem cells cause induction of granulocyte differentiation of rat bone marrow C-kit+ hematopoietic stem cells through JAK3/STAT3, ERK, and …

E Fathi, SA Mesbah-Namin, I Vietor… - Iranian journal of basic …, 2022 - ncbi.nlm.nih.gov
Objective (s): Hematopoietic stem cells (HSCs) are the cells that give rise to different types of
blood cells during the hematopoiesis process. Mesenchymal stromal cells (MSCs) as key …

Mesenchymal stem cells could be considered as a candidate for further studies in cell-based therapy of Alzheimer's disease via targeting the signaling pathways

R Farahzadi, E Fathi, I Vietor - ACS chemical neuroscience, 2020 - ACS Publications
Mesenchymal stem cells (MSCs) are of particular interest because of their potential in
regenerative medicine. Stem cell-based therapies cast a new hope for neurodegenerative …

[HTML][HTML] The functional mechanism of bone marrow-derived mesenchymal stem cells in the treatment of animal models with Alzheimer's disease: crosstalk between …

C Qin, L Bai, Y Li, K Wang - Stem cell research & therapy, 2022 - Springer
The transplantation of bone marrow-derived mesenchymal stem cells (BMMSCs) alleviates
neuropathology and improves cognitive deficits in animal models with Alzheimer's disease …

Cardiac differentiation of bone-marrow-resident c-kit+ stem cells by L-carnitine increases through secretion of VEGF, IL6, IGF-1, and TGF-β as clinical agents in …

E Fathi, R Farahzadi, I Vietor, S Javanmardi - Journal of biosciences, 2020 - Springer
The idea of regenerating lost myocardium via cell-based therapies remains as highly
considerable. C-kit+ stem/progenitor cells are represented to be suitable candidates for …

Signaling crosstalk between mesenchymal stem cells and tumor cells: Implications for tumor suppression or progression

M Taheri, HA Tehrani, S Dehghani… - Cytokine & Growth …, 2024 - Elsevier
Mesenchymal stem cells (MSCs) have been extensively used in various therapeutic
applications over the last two decades, particularly in regenerative medicine and cancer …

Functional mechanism of bone marrow-derived mesenchymal stem cells in the treatment of animal models with Alzheimer's disease: inhibition of neuroinflammation

C Qin, Y Li, K Wang - Journal of inflammation research, 2021 - Taylor & Francis
The transplantation of bone marrow-derived mesenchymal stem cells (BMMSCs) alleviates
neuropathology and improves cognitive deficits in animal models with Alzheimer's disease …

[HTML][HTML] Toll-like receptor 4 activates the NLRP3 inflammasome pathway and periodontal inflammaging by inhibiting Bmi-1 expression

ZY Qin, X Gu, YL Chen, JB Liu… - International …, 2021 - spandidos-publications.com
Overproduction of pro-inflammatory cytokines in the aged, which is called inflammaging,
leads to the deterioration of periodontitis. Toll-like receptor 4 (TLR4) plays a role in the …

[HTML][HTML] Mesenchymal stem cells in acute myeloid leukemia: a focus on mechanisms involved and therapeutic concepts

E Fathi, Z Sanaat, R Farahzadi - Blood research, 2019 - synapse.koreamed.org
Drug resistance in cancer, especially in leukemia, creates a dilemma in treatment planning.
Consequently, studies related to the mechanisms underlying drug resistance, the molecular …