Risk factors for hepatitis C virus (HCV) infection vary, and there were an estimated 1.75
million new cases worldwide in 2015. The World Health Organization aims for a 90 …

Viral hepatitis, secondary to infection with hepatitis A, B, C, D, and E viruses, are a major
public health problem and an important cause of morbidity and mortality. Despite the huge …

Mucosal-associated invariant T (MAIT) cells are innate sensors of viruses and can augment
early immune responses and contribute to protection. We hypothesized that MAIT cells may …

Introduction: Precision medicine is the concept of treating diseases based on environmental
factors, lifestyles, and molecular profiles of patients. This approach has been found to …

There is consensus that hepatitis C virus-specific T cells play a central role in the outcome,
clearance versus persistence, of acute infection and that they contribute to protection against …

Introduction Due to overcome the hardness of the vaccine design, computational
vaccinology is emerging widely. Prediction of T cell and B cell epitopes, antigen processing …

An estimated 1.5–2 million new hepatitis C virus (HCV) infections occur globally each year.
Critical to the World Health Organization's (WHO) HCV elimination strategy is an 80 …

Replication-deficient adenoviral vectors have been under investigation as a platform
technology for vaccine development for several years and have recently been successfully …

A functional adaptive immune response is the major determinant for clearance of hepatitis C
virus (HCV) infection. However, in the majority of patients, this response fails and persistent …

Viruses have threatened human lives for decades, causing both chronic and acute infections
accompanied by mild to severe symptoms. During the long journey of confrontation, humans …