Macromolecular biomolecules are currently dethroning classical small molecule
therapeutics because of their improved targeting and delivery properties. Protamine-a small …

Therapeutic proteins are well-tolerated bioactive compounds used in different therapies, due
to its high specificity and biopotency. Nevertheless, they may also present some …

Mycobacterium tuberculosis has thrived in parallel with humans for millennia, and despite
our efforts, M. tuberculosis continues to plague us, currently infecting a third of the world's …

The nitrate/nitrite response regulatory protein NarL belongs to the two-component regulatory
system of Mycobacterium tuberculosis (MTB), plays a crucial role in anaerobic survival of …

The pe/ppe genes are found in pathogenic, slow-growing Mycobacterium tuberculosis and
other M. tuberculosis complex (MTBC) species. These genes are considered key factors in …

The advances in the development of drugs and vaccines for major infectious diseases of
tuberculosis (TB), malaria and HIV represent some of the most significant milestones in their …

Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis
(Mtb), and its incidence and mortality are increasing. The BCG vaccine was developed in the …

The PE/PPE proteins encoded by seven percent (7%) of Mycobacterium tuberculosis (Mtb)
genome are the chief constituents to pathogen's virulence reservoir. The fact that these …

Liposomes, lipid-based vesicular systems, have attracted major interest as a means to
improve drug delivery to various organs and tissues in the human body. Recent literature …

Tuberculosis (TB) classified as one of the most fatal contagious diseases is of prime concern
globally. Mycobacterium tuberculosis is the causative agent that ingresses within the host …