Advances in biosynthesis, regulation, and metabolic engineering of plant specialized terpenoids

DA Nagegowda, P Gupta - Plant Science, 2020 - Elsevier
Plant specialized terpenoids are natural products that have no obvious role in growth and
development, but play many important functional roles to improve the plant's overall fitness …

Biosynthesis of essential oils in aromatic plants: A review

R Rehman, MA Hanif, Z Mushtaq… - Food Reviews …, 2016 - Taylor & Francis
In aromatic plants species, biosynthesis of essential oils occurs through two complex natural
biochemical pathways involving different enzymatic reactions. Isopentenyl diphosphate …

The seco-iridoid pathway from Catharanthus roseus

K Miettinen, L Dong, N Navrot, T Schneider… - Nature …, 2014 - nature.com
The (seco) iridoids and their derivatives, the monoterpenoid indole alkaloids (MIAs), form
two large families of plant-derived bioactive compounds with a wide spectrum of high-value …

The complete functional characterisation of the terpene synthase family in tomato

F Zhou, E Pichersky - New Phytologist, 2020 - Wiley Online Library
Analysis of the updated reference tomato genome found 34 full‐length TPS genes and 18
TPS pseudogenes. Biochemical analysis has now identified the catalytic activities of all …

Maize resistance to witchweed through changes in strigolactone biosynthesis

C Li, L Dong, J Durairaj, JC Guan, M Yoshimura… - Science, 2023 - science.org
Maize (Zea mays) is a major staple crop in Africa, where its yield and the livelihood of
millions are compromised by the parasitic witchweed Striga. Germination of Striga is …

Manipulation of GES and ERG20 for geraniol overproduction in Saccharomyces cerevisiae

GZ Jiang, MD Yao, Y Wang, L Zhou, TQ Song, H Liu… - Metabolic …, 2017 - Elsevier
Manipulation of monoterpene synthases to maximize flux towards targeted products from
GPP (geranyl diphosphate) is the main challenge for heterologous monoterpene …

Natural variation in monoterpene synthesis in kiwifruit: transcriptional regulation of terpene synthases by NAC and ETHYLENE-INSENSITIVE3-like transcription factors

NJ Nieuwenhuizen, X Chen, MY Wang… - Plant …, 2015 - academic.oup.com
Two kiwifruit (Actinidia) species with contrasting terpene profiles were compared to
understand the regulation of fruit monoterpene production. High rates of terpinolene …

Engineered mitochondrial production of monoterpenes in Saccharomyces cerevisiae

DA Yee, AB DeNicola, JM Billingsley, JG Creso… - Metabolic …, 2019 - Elsevier
Monoterpene indole alkaloids (MIAs) from plants encompass a broad class of structurally
complex and medicinally valuable natural products. MIAs are biologically derived from the …

Monoterpenoid indole alkaloids biosynthesis and its regulation in Catharanthus roseus: a literature review from genes to metabolites

Q Pan, NR Mustafa, K Tang, YH Choi… - Phytochemistry reviews, 2016 - Springer
As the only source for the low-abundance antitumor agents vinblastine and vincristine,
Catharanthus roseus is highly valued and has been studied extensively as a model for …

Engineering Escherichia coli for production of geraniol by systematic synthetic biology approaches and laboratory-evolved fusion tags

X Wang, J Chen, J Zhang, Y Zhou, Y Zhang… - Metabolic …, 2021 - Elsevier
Geraniol is a valuable monoterpene extensively used in the fragrance, food, and cosmetic
industries. Increasing environmental concerns and supply gaps have motivated efforts to …