A critical overview of targeted therapies for glioblastoma

KK Jain - Frontiers in oncology, 2018 - frontiersin.org
Over the past century, treatment of malignant tumors of the brain has remained a challenge.
Refinements in neurosurgical techniques, discovery of powerful chemotherapeutic agents …

Baculovirus: an insect-derived vector for diverse gene transfer applications

KJ Airenne, YC Hu, TA Kost, RH Smith, RM Kotin… - Molecular Therapy, 2013 - cell.com
Insect-derived baculoviruses have emerged as versatile and safe workhorses of
biotechnology. Baculovirus expression vectors (BEVs) have been applied widely for crop …

[HTML][HTML] Human embryonic stem cell-derived mesenchymal stem cells improved premature ovarian failure

K Bahrehbar, MR Valojerdi, F Esfandiari… - World journal of stem …, 2020 - ncbi.nlm.nih.gov
BACKGROUND Premature ovarian failure (POF) affects many adult women less than 40
years of age and leads to infertility. According to previous reports, various tissue-specific …

Emerging insights into barriers to effective brain tumor therapeutics

GF Woodworth, GP Dunn, EA Nance, J Hanes… - Frontiers in …, 2014 - frontiersin.org
There is great promise that ongoing advances in the delivery of therapeutics to the central
nervous system (CNS) combined with rapidly expanding knowledge of brain tumor patho …

Macrophage-associated mesenchymal stem cells assume an activated, migratory, pro-inflammatory phenotype with increased IL-6 and CXCL10 secretion

K Anton, D Banerjee, J Glod - PloS one, 2012 - journals.plos.org
Mesenchymal stem cells (MSCs) exhibit tropism for sites of tissue injury and tumors.
However, the influence of the microenvironment on MSC phenotype and localization …

Gene delivery approaches for mesenchymal stem cell therapy: strategies to increase efficiency and specificity

GS Oggu, S Sasikumar, N Reddy, KKR Ella… - Stem cell reviews and …, 2017 - Springer
A significant number of clinical trials have been undertaken to explore the use of
mesenchymal stem cells (MSCs) for the treatment of several diseases such as Crohn's …

Selective ablation of tumorigenic cells following human induced pluripotent stem cell-derived neural stem/progenitor cell transplantation in spinal cord injury

K Kojima, H Miyoshi, N Nagoshi… - Stem Cells …, 2019 - academic.oup.com
Tumorigenesis is an important problem that needs to be addressed in the field of human
stem/progenitor cell transplantation for the treatment of subacute spinal cord injury (SCI) …

Do mesenchymal stem cells function across species barriers? Relevance for xenotransplantation

J Li, MB Ezzelarab, DKC Cooper - Xenotransplantation, 2012 - Wiley Online Library
Li J, Ezzelarab MB, Cooper DKC. Do mesenchymal stem cells function across species
barriers? Relevance for xenotransplantation. Xenotransplantation 2012; 19: 273–285.© …

Conditioned media from human adipose tissue‐derived mesenchymal stem cells and umbilical cord‐derived mesenchymal stem cells efficiently induced the apoptosis …

C Yang, D Lei, W Ouyang, J Ren, H Li… - BioMed research …, 2014 - Wiley Online Library
Human mesenchymal stem cells (MSCs) have an intrinsic property for homing towards
tumor sites and can be used as tumor‐tropic vectors for tumor therapy. But very limited …

Advanced cell therapies for glioblastoma

G Wang, W Wang - Frontiers in Immunology, 2022 - frontiersin.org
The sheer ubiquity of Gioblastoma (GBM) cases would lead you to believe that there should
have been many opportunities for the discovery of treatments to successfully render it into …