Plant-derived anticancer compounds as new perspectives in drug discovery and alternative therapy

CA Dehelean, I Marcovici, C Soica, M Mioc… - Molecules, 2021 - mdpi.com
Despite the recent advances in the field of chemically synthetized pharmaceutical agents,
nature remains the main supplier of bioactive molecules. The research of natural products is …

Gold nanostructures in melanoma: advances in treatment, diagnosis, and theranostic applications

ZS Dastgheib, SS Abolmaali, G Farahavar… - Heliyon, 2024 - cell.com
Melanoma, a lethal form of skin cancer, poses a significant challenge in oncology due to its
aggressive nature and high mortality rates. Gold nanostructures, including gold …

Nanomedicine: A pragmatic approach for tackling melanoma skin cancer

VM Prajapat, S Mahajan, PG Paul, M Aalhate… - Journal of Drug Delivery …, 2023 - Elsevier
Melanoma is the most aggressive form of skin cancer and its annual incidence rates are
increasing globally. Though chemotherapy, radiotherapy, immunotherapy and targeted …

The optimized delivery of triterpenes by liposomal nanoformulations: Overcoming the challenges

A Milan, A Mioc, A Prodea, M Mioc, R Buzatu… - International journal of …, 2022 - mdpi.com
The last decade has witnessed a sustained increase in the research development of modern-
day chemo-therapeutics, especially for those used for high mortality rate pathologies …

Nanoparticle-Based Treatment Approaches for Skin Cancer: A Systematic Review

MJ Diaz, N Natarelli, S Aflatooni, SJ Aleman… - Current …, 2023 - mdpi.com
Nanoparticles have shown marked promise as both antineoplastic agents and drug carriers.
Despite strides made in immunomodulation, low success rates and toxicity remain …

Present scenario of bioconjugates in cancer therapy: a review

A Wadhawan, M Chatterjee, G Singh - International Journal of Molecular …, 2019 - mdpi.com
Cancer is one of the deadliest diseases and poses a risk to people all over the world.
Surgery, chemo, and radiation therapy have been the only options available until today to …

Chitosan gold nanoparticles induce different ROS-dependent cell death modalities in leukemic cells

AC Martínez-Torres, HY Lorenzo-Anota… - International Journal …, 2019 - Taylor & Francis
Background Nanotechnology proposes the use of gold nanoparticles (AuNPs) for drug
delivery, diagnosis, and treatment of cancer. Leukemia is a type of hematopoietic cancer that …

Pleiotropic effects of eugenol: The good, the bad, and the unknown

OM Aburel, IZ Pavel, MD Dănilă, T Lelcu… - Oxidative medicine …, 2021 - Wiley Online Library
Phytocompounds and medicinal herbs were used in traditional ancient medicine and are
nowadays increasingly screened in both experimental and clinical settings due to their …

Fe3O4 Nanoparticles in Combination with 5-FU Exert Antitumor Effects Superior to Those of the Active Drug in a Colon Cancer Cell Model

S Genc, A Taghizadehghalehjoughi, Y Yeni… - Pharmaceutics, 2023 - mdpi.com
(1) Background: Colon cancer is one of the most common cancer types, and treatment
options, unfortunately, do not continually improve the survival rate of patients. With the …

Synthesis and characterization of gold nanoparticles and their toxicity in alternative methods to the use of mammals

MY Marcelino, FA Borges, L Scorzoni… - Journal of …, 2021 - Elsevier
In this work we synthesize and characterize AuNPs using two chemical routes: via sodium
citrate and via sodium citrate/borohydride. The cytotoxicity of AuNPs was tested by …