Single nucleotide polymorphisms (SNPs) are the most frequent type of genetic alterations
between individuals. An SNP located within the coding sequence of a gene may lead to an …

Over the past few decades, the incidence of cancer has rapidly increased all over the world
and cancer remains a major threat to public health. It is believed that cancer results from a …

Background: Genetic polymorphisms in DNA repair genes may influence individual variation
in DNA repair capacity and may play an important role in carcinogenesis. We investigated …

Background XRCC4 is a NHEJ factor identified recently that plays a vital role in repairing
DNA double-stranded breaks. Studies have reported the associations between abnormal …

X‐ray repair complementing group 4 (XRCC4) is very important in maintaining overall
genome stability and may play an important role in carcinogenesis. We aimed to investigate …

Abstract Exonuclease 1 (Exo1) is an important nuclease involved in the mismatch repair
system that contributes to the maintenance of genomic stability, modulation of DNA …

Background: The DNA repair gene XRCC4, a member of NHEJ for double strand breaks, is
very important in maintaining the overall genome stability, and may play an important role in …

Exonuclease 1 (Exo1) is an important nuclease involved in the mismatch repair system that
helps to maintain genomic stability, to modulate DNA recombination, and to mediate cell …

Genetic polymorphisms in DNA repair genes may influence individual variation in DNA
repair capacity, which may be associated with risk of gastric antrum adenocarcinoma (GAA) …

Background Our previous investigations have shown that the variants of X-ray repair
complementing 4 (XRCC4) may be involved in hepatocellular carcinoma (hepatocarcinoma) …