Single nucleotide polymorphisms in DNA repair genes and putative cancer risk
B Köberle, B Koch, BM Fischer, A Hartwig - Archives of toxicology, 2016 - Springer
Single nucleotide polymorphisms (SNPs) are the most frequent type of genetic alterations
between individuals. An SNP located within the coding sequence of a gene may lead to an …
between individuals. An SNP located within the coding sequence of a gene may lead to an …
Role of the XRCC5/XRCC6 dimer in carcinogenesis and pharmacogenomics
Over the past few decades, the incidence of cancer has rapidly increased all over the world
and cancer remains a major threat to public health. It is believed that cancer results from a …
and cancer remains a major threat to public health. It is believed that cancer results from a …
Genetic polymorphisms in DNA repair genes XRCC4 and XRCC5 and aflatoxin b1–related hepatocellular carcinoma
XD Long, D Zhao, C Wang, XY Huang, JG Yao… - …, 2013 - journals.lww.com
Background: Genetic polymorphisms in DNA repair genes may influence individual variation
in DNA repair capacity and may play an important role in carcinogenesis. We investigated …
in DNA repair capacity and may play an important role in carcinogenesis. We investigated …
[HTML][HTML] Systematic analysis identifies XRCC4 as a potential immunological and prognostic biomarker associated with pan-cancer
Y Yu, Y Sun, Z Li, J Li, D Tian - BMC bioinformatics, 2023 - Springer
Background XRCC4 is a NHEJ factor identified recently that plays a vital role in repairing
DNA double-stranded breaks. Studies have reported the associations between abnormal …
DNA double-stranded breaks. Studies have reported the associations between abnormal …
[PDF][PDF] Polymorphisms in the coding region of X‐ray repair complementing group 4 and aflatoxin B1‐related hepatocellular carcinoma
XD Long, JG Yao, Z Zeng, Y Ma, XY Huang… - …, 2013 - Wiley Online Library
X‐ray repair complementing group 4 (XRCC4) is very important in maintaining overall
genome stability and may play an important role in carcinogenesis. We aimed to investigate …
genome stability and may play an important role in carcinogenesis. We aimed to investigate …
[PDF][PDF] Single-nucleotide polymorphism of the Exo1 gene: association with gastric cancer susceptibility and interaction with smoking in Taiwan
Abstract Exonuclease 1 (Exo1) is an important nuclease involved in the mismatch repair
system that contributes to the maintenance of genomic stability, modulation of DNA …
system that contributes to the maintenance of genomic stability, modulation of DNA …
Significant association of an XRCC4 single nucleotide polymorphism with bladder cancer susceptibility in Taiwan
CH Chang, CL Chang, CW Tsai, HC Wu… - Anticancer …, 2009 - ar.iiarjournals.org
Background: The DNA repair gene XRCC4, a member of NHEJ for double strand breaks, is
very important in maintaining the overall genome stability, and may play an important role in …
very important in maintaining the overall genome stability, and may play an important role in …
Interaction of Exo1 genotypes and smoking habit in oral cancer in Taiwan
MH Tsai, HC Tseng, CS Liu, CL Chang, CW Tsai… - Oral oncology, 2009 - Elsevier
Exonuclease 1 (Exo1) is an important nuclease involved in the mismatch repair system that
helps to maintain genomic stability, to modulate DNA recombination, and to mediate cell …
helps to maintain genomic stability, to modulate DNA recombination, and to mediate cell …
Genetic polymorphisms in DNA repair genes XPC, XPD, and XRCC4, and susceptibility to Helicobacter pylori infection‐related gastric antrum adenocarcinoma in …
XD Long, Y Ma, YZ Huang, Y Yi… - … in cooperation with …, 2010 - Wiley Online Library
Genetic polymorphisms in DNA repair genes may influence individual variation in DNA
repair capacity, which may be associated with risk of gastric antrum adenocarcinoma (GAA) …
repair capacity, which may be associated with risk of gastric antrum adenocarcinoma (GAA) …
[HTML][HTML] Prognostic significance of XRCC4 expression in hepatocellular carcinoma
J Lu, XZ Wang, TQ Zhang, XY Huang, JG Yao… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Background Our previous investigations have shown that the variants of X-ray repair
complementing 4 (XRCC4) may be involved in hepatocellular carcinoma (hepatocarcinoma) …
complementing 4 (XRCC4) may be involved in hepatocellular carcinoma (hepatocarcinoma) …