Working memory is the ability to maintain and manipulate information in the conscious mind
over a timescale of seconds. This ability is thought to be maintained through the persistent …

Working memory (WM), a core cognitive function, enables the temporary holding and
manipulation of information in mind to support ongoing behavior. Neurophysiological …

The prefrontal cortex maintains information in memory through static or dynamic population
codes depending on task demands, but whether the population coding schemes used are …

Training in working memory tasks is associated with lasting changes in prefrontal cortical
activity. To assess the neural activity changes induced by training, we recorded single units …

Alzheimer's disease (AD) is a major cause of dementia, with the number of patients with this
condition anticipated to exceed 50 million worldwide in the near future. Despite extensive …

Neurons in parietal cortex exhibit task-related activity during decision-making tasks.
However, it remains unclear how long-term training to perform different tasks over months or …

Rapid progress in our understanding of the brain's learning mechanisms has been
accomplished over the past decade, particularly with conceptual advances, including …

Neurons in the dorsolateral prefrontal cortex (dlPFC) and posterior parietal cortex (PPC) are
activated by different cognitive tasks and respond differently to the same stimuli depending …

Working memory ability continues to mature into adulthood in humans and nonhuman
primates. At the single-neuron level, adolescent development is characterized by increased …

Performing working memory tasks correctly requires not only the temporary maintenance of
information but also the visual-to-motor transformation of information. Although sustained …