The genus Mycobacterium contains several slow-growing human pathogens, including
Mycobacterium tuberculosis, Mycobacterium leprae, and Mycobacterium avium …

The remarkable ability of Mycobacterium tuberculosis to survive attacks from the host
immune response and drug treatment is due to the resilience of a few bacilli rather than a …

The widespread use of antibiotics has placed bacterial pathogens under intense pressure to
evolve new survival mechanisms. Genomic analysis of 51,229 Mycobacterium tuberculosis …

Genetic interactions identify functional connections between genes and pathways,
establishing gene functions or druggable targets. Here we use CRISPRi–TnSeq, CRISPRi …

Mycobacterium abscessus (Mab) is a rapidly growing non-tuberculous mycobacterium
(NTM) that causes a wide range of infections. Treatment of Mab infections is difficult because …

The movement of lipids within and between membranes in bacteria is essential for building
and maintaining the bacterial cell envelope. Moving lipids to their final destination is often …

Introduction Mycobacteria assemble a complex cell wall with cross-linked peptidoglycan
(PG) which plays an essential role in maintenance of cell wall integrity and tolerance to …

The intracellular membrane domain (IMD) is a laterally discrete region of the mycobacterial
plasma membrane, enriched in the subpolar region of the rod-shaped cell. Here, we report …

Mycobacterium smegmatis (M. sm) is frequently used as an alternative model organism in
Mycobacterium tuberculosis (M. tb) studies. While containing high sequence homology with …

Abstract The Many Hosts of Mycobacteria (MHM) meeting series brings together basic
scientists, clinicians and veterinarians to promote robust discussion and dissemination of …