Emodin-A natural anthraquinone derivative with diverse pharmacological activities

RB Semwal, DK Semwal, S Combrinck, A Viljoen - Phytochemistry, 2021 - Elsevier
Abstract Emodin (1, 3, 8-trihydroxy-6-methyl-anthraquinone) is a natural anthraquinone
derivative that is present in numerous globally renowned herbal medicines. It is recognised …

Chemistry and pharmacology of oxyprenylated secondary plant metabolites

F Epifano, S Genovese, L Menghini, M Curini - Phytochemistry, 2007 - Elsevier
Oxyprenylated natural products (isopentenyloxy-, geranyloxy-and the less spread
farnesyloxy-compounds and their biosynthetic derivatives) represent a family of secondary …

In silico identification of potential inhibitors of key SARS-CoV-2 3CL hydrolase (Mpro) via molecular docking, MMGBSA predictive binding energy calculations, and …

MI Choudhary, M Shaikh, A tul-Wahab, A ur-Rahman - Plos one, 2020 - journals.plos.org
The incidence of 2019 novel corona virus (SARS-CoV-2) has created a medical emergency
throughout the world. Various efforts have been made to develop the vaccine or effective …

Fruitful decade for antileishmanial compounds from 2002 to late 2011

H Hussain, A Al-Harrasi, A Al-Rawahi, IR Green… - Chemical …, 2014 - ACS Publications
Leishmaniasis, usually caused by the genus Leishmania, has not received the attention it
deserves and in recent times has developed into a major health problem worldwide. 1, 2 …

Antimalarial activity of plant metabolites

WH Pan, XY Xu, N Shi, SW Tsang… - International Journal of …, 2018 - mdpi.com
Malaria, as a major global health problem, continues to affect a large number of people each
year, especially those in developing countries. Effective drug discovery is still one of the …

Ethnobotanical survey on medicinal plants used by Guinean traditional healers in the treatment of malaria

MS Traore, MA Baldé, MST Diallo, ES Baldé… - Journal of …, 2013 - Elsevier
Ethnopharmacological relevance The objective of the present study was to collect and
document information on herbal remedies traditionally used for the treatment of malaria in …

Natural products from plants as drug candidates and lead compounds against leishmaniasis and trypanosomiasis

MM Salem, KA Werbovetz - Current medicinal chemistry, 2006 - ingentaconnect.com
Millions of people in the developing world are affected by diseases caused by the
kinetoplastid parasites: the leishmaniases, African trypanosomiasis, and Chagas disease. In …

The phytochemistry and pharmacology of three Rheum species: A comprehensive review with future perspectives

X Yang, L Dai, F Yan, Y Ma, X Guo, J Jenis, Y Wang… - Phytomedicine, 2024 - Elsevier
Background Rheum palmatum, R. tanguticum, and R. officinale, integral species of the
genus Rheum, are widely used across global temperate and subtropical regions. These …

Isoneocryptolepine, a synthetic indoloquinoline alkaloid, as an antiplasmodial lead compound

S Van Miert, S Hostyn, BUW Maes… - Journal of natural …, 2005 - ACS Publications
The antiprotozoal activities of three naturally occurring isomeric indoloquinoline alkaloids,
ie, cryptolepine (1), neocryptolepine (2), and isocryptolepine (3), and two dimeric …

Antimicrobial structure activity relationship of five anthraquinones of emodine type isolated from Vismia laurentii

GA Kemegne, P Mkounga, JJ Essia Ngang… - BMC microbiology, 2017 - Springer
Background Antimicrobial activity of anthraquinone compounds of emodine type has been
reported by many authors. These compounds are found in Vismia laurentii (Clusiaceae), a …