Interaction modes and approaches to glycopeptide and glycoprotein enrichment
Protein glycosylation has received increased attention for its critical role in cell biology and
diseases. Developing new methodologies to discern phenotype-dependent glycosylation …
diseases. Developing new methodologies to discern phenotype-dependent glycosylation …
Counterion optimization dramatically improves selectivity for phosphopeptides and glycopeptides in electrostatic repulsion-hydrophilic interaction chromatography
A well-hydrated counterion can selectively and dramatically increase retention of a charged
analyte in hydrophilic interaction chromatography. The effect is enhanced if the column is …
analyte in hydrophilic interaction chromatography. The effect is enhanced if the column is …
Finding the sweet spot in ERLIC mobile phase for simultaneous enrichment of N-glyco and phosphopeptides
Simultaneous enrichment of glyco-and phosphopeptides will benefit the studies of biological
processes regulated by these posttranslational modifications (PTMs). It will also reveal …
processes regulated by these posttranslational modifications (PTMs). It will also reveal …
Quantitative phosphoproteomics of the human neural stem cell differentiation into oligodendrocyte by mass spectrometry
Cellular processes such as proliferation, differentiation, and adaptation to environmental
changes are regulated by protein phosphorylation. In order to enhance the understanding of …
changes are regulated by protein phosphorylation. In order to enhance the understanding of …
The use of electrostatic repulsion-hydrophilic interaction chromatography (ERLIC) for proteomics research
Characterization and studies of proteome are challenging because biological samples are
complex, with a wide dynamic range of abundance. At present the proteins are identified by …
complex, with a wide dynamic range of abundance. At present the proteins are identified by …