The emerging antioxidant paradigm of mesenchymal stem cell therapy

R Stavely, K Nurgali - Stem Cells Translational Medicine, 2020 - academic.oup.com
Mesenchymal stem cells (multipotent stromal cells; MSCs) have been under investigation for
the treatment of diverse diseases, with many promising outcomes achieved in animal …

Stem cells: a promising candidate to treat neurological disorders

CG Song, YZ Zhang, HN Wu, XL Cao… - Neural regeneration …, 2018 - journals.lww.com
Neurologic impairments are usually irreversible as a result of limited regeneration in the
central nervous system. Therefore, based on the regenerative capacity of stem cells …

The therapeutic potential of mesenchymal stem cell–derived exosomes in treatment of neurodegenerative diseases

AM Gorabi, N Kiaie, GE Barreto, MI Read, HA Tafti… - Molecular …, 2019 - Springer
Neurologic complications are commonly regarded as irreversible impairments that stem from
limited potential of regeneration of the central nervous system (CNS). On the other side, the …

Metabolic and inflammatory adaptation of reactive astrocytes: role of PPARs

J Iglesias, L Morales, GE Barreto - Molecular neurobiology, 2017 - Springer
Astrocyte-mediated inflammation is associated with degenerative pathologies such as
Alzheimer's and Parkinson's diseases and multiple sclerosis. The acute inflammation and …

[HTML][HTML] Mesenchymal stromal cell secretome for traumatic brain injury: Focus on immunomodulatory action

F Pischiutta, E Caruso, H Cavaleiro, AJ Salgado… - Experimental …, 2022 - Elsevier
The severity and long-term consequences of brain damage in traumatic brain injured (TBI)
patients urgently calls for better neuroprotective/neuroreparative strategies for this …

What's new in traumatic brain injury: update on tracking, monitoring and treatment

C Reis, Y Wang, O Akyol, WM Ho… - International journal of …, 2015 - mdpi.com
Traumatic brain injury (TBI), defined as an alteration in brain functions caused by an external
force, is responsible for high morbidity and mortality around the world. It is important to …

Mesenchymal stem cells in the treatment of traumatic brain injury

A Hasan, G Deeb, R Rahal, K Atwi, S Mondello… - Frontiers in …, 2017 - frontiersin.org
Traumatic brain injury (TBI) is characterized by a disruption in the normal function of the
brain due to an injury following a trauma, which can potentially cause severe physical …

The TRIM protein Mitsugumin 53 enhances survival and therapeutic efficacy of stem cells in murine traumatic brain injury

F Guan, T Huang, X Wang, Q Xing, K Gumpper… - Stem cell research & …, 2019 - Springer
Background Traumatic brain injury (TBI) is a common neurotrauma leading to brain
dysfunction and death. Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) …

Secretome of mesenchymal stem cells and its potential protective effects on brain pathologies

E Baez-Jurado, O Hidalgo-Lanussa… - Molecular …, 2019 - Springer
Previous studies have indicated that mesenchymal stem cells (MSCs) have a fundamental
role in the repair and regeneration of damaged tissues. There is strong evidence showing …

Comparison of human mesenchymal stromal cells from four neonatal tissues: amniotic membrane, chorionic membrane, placental decidua and umbilical cord

AB Araújo, GD Salton, JM Furlan, N Schneider… - Cytotherapy, 2017 - Elsevier
Abstract Background Mesenchymal stromal cells (MSCs) are being investigated as a
potential alternative for cellular therapy. This study was designed to compare the biological …