Genetic variation in resistance to mixed, predominantly Teladorsagia circumcincta nematode infections of sheep: from heritabilities to gene identification

MJ Stear, B Boag, I Cattadori, L Murphy - Parasite immunology, 2009 - Wiley Online Library
In cool temperate areas, such as Scotland, sheep are infected by a variety of nematodes but
the dominant nematode is Teladorsagia circumcincta. Resistant animals have one or more …

Small ruminant resistance against gastrointestinal nematodes: a case of Haemonchus contortus

HA Saddiqi, A Jabbar, M Sarwar, Z Iqbal… - Parasitology …, 2011 - Springer
Gastrointestinal nematode (GIN) infections are a common constraint to small ruminant
industry throughout the world, and among those, haemonchosis has its own significance …

Identifying hepatic genes regulating the ovine response to gastrointestinal nematodes using RNA-Sequencing

S Dixon, NA Karrow, E Borkowski… - Frontiers in …, 2023 - frontiersin.org
Gastrointestinal nematode (GIN) infections are considered the most important disease of
grazing sheep and due to increasing anthelmintic resistance, chemical control alone is …

MHC class II DRB1 gene polymorphism in the pathogenesis of Maedi–Visna and pulmonary adenocarcinoma viral diseases in sheep

A Larruskain, E Minguijón, K García-Etxebarria… - Immunogenetics, 2010 - Springer
Ovine pulmonary adenocarcinoma (OPA) and Maedi–Visna (Maedi) are two chronic
respiratory diseases of retroviral origin which occur worldwide. It is known that different host …

Genome-wide association study of footrot in Texel sheep

S Mucha, L Bunger, J Conington - Genetics Selection Evolution, 2015 - Springer
Background This is the first study based on a genome-wide association approach that
investigates the links between ovine footrot scores and molecular polymorphisms in Texel …

The influence of MHC and immunoglobulins A and E on host resistance to gastrointestinal nematodes in sheep

CY Lee, KA Munyard, K Gregg… - Journal of …, 2011 - Wiley Online Library
Gastrointestinal nematode parasites in farmed animals are of particular importance due to
their effects on production. In Australia, it is estimated that the direct and indirect effects of …

An explicit immunogenetic model of gastrointestinal nematode infection in sheep

J Prada Jiménez de Cisneros… - Journal of the …, 2014 - royalsocietypublishing.org
Gastrointestinal nematodes are a global cause of disease and death in humans, wildlife and
livestock. Livestock infection has historically been controlled with anthelmintic drugs, but the …

Breeding for disease resistance in livestock and fish.

MJ Stear, G Nikbakht, L Matthews… - CABI Reviews, 2012 - cabidigitallibrary.org
Breeding for disease resistance offers improved animal welfare and increased returns for
breeders. It is now practised in cattle, sheep, pig, chicken and fish farming. This review …

Association of MHC class II haplotypes with reduced faecal nematode egg count and IgA activity in British Texel sheep

AOA Ali, L Murphy, A Stear, K Fairlie‐Clarke… - Parasite …, 2019 - Wiley Online Library
Nematode infection is one of the principal diseases suffered by sheep and the class II region
of the MHC has been repeatedly associated with differences in susceptibility and resistance …

Divergent allele advantage provides a quantitative model for maintaining alleles with a wide range of intrinsic merits

T Stefan, L Matthews, JM Prada, C Mair, R Reeve… - Genetics, 2019 - academic.oup.com
A striking feature of the antigen coding genes of the Major Histocompatibility Complex
(MHC) is their genetic diversity. However, the exact mechanisms maintaining this diversity …