Biomarker discovery and implementation are at the forefront of the precision medicine
movement. Modern advances in the field of metabolomics afford the opportunity to readily …

Carnitine is a conditionally essential nutrient that plays a vital role in energy production and
fatty acid metabolism. Vegetarians possess a greater bioavailability than meat eaters …

Carnitine is an amino acid-derived substance that coordinates a wide range of biological
processes. Such functions include transport of long-chain fatty acids from the cytoplasm to …

Sepsis and multiple organ dysfunction syndrome (MODS) are major causes of morbidity and
mortality in the intensive care unit. Recently mitochondrial dysfunction has been proposed …

Methotrexate (MTX), a folic acid antagonist widely used for the treatment of a variety of
tumors and inflammatory diseases, affects normal tissues that have a high rate of …

Metabolomics based on mass spectrometry represents an innovative approach to
characterize multifactorial diseases, such as multiple sclerosis (MuS). To date, the most …

Background In a recently published paper, Harvey and Wessely put forward
a'biopsychosocial'explanatory model for myalgic encephalomyelitis/chronic fatigue …

Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disorder that is
clinically complex and has increased production of autoantibodies. Via emerging …

The testis is an immunologically privileged organ. Sertoli cells can form a blood‐testis
barrier and protect sperm cells from self‐immune system attacks. Spermatogenesis may be …

Background The mechanism (s) underlying the effects of l-carnitine (β-hydroxy-γ-N-
trimethylammonium-butyrate; LC) in cardiovascular diseases are not well clarified. Previous …