TEER measurement techniques for in vitro barrier model systems
Transepithelial/transendothelial electrical resistance (TEER) is a widely accepted
quantitative technique to measure the integrity of tight junction dynamics in cell culture …
quantitative technique to measure the integrity of tight junction dynamics in cell culture …
[HTML][HTML] Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's disease
AR Nelson, MD Sweeney, AP Sagare… - Biochimica et Biophysica …, 2016 - Elsevier
Vascular insults can initiate a cascade of molecular events leading to neurodegeneration,
cognitive impairment, and dementia. Here, we review the cellular and molecular …
cognitive impairment, and dementia. Here, we review the cellular and molecular …
Cerebral hypoperfusion and glucose hypometabolism: Key pathophysiological modulators promote neurodegeneration, cognitive impairment, and Alzheimer's …
MA Daulatzai - Journal of neuroscience research, 2017 - Wiley Online Library
Aging, hypertension, diabetes, hypoxia/obstructive sleep apnea (OSA), obesity, vitamin
B12/folate deficiency, depression, and traumatic brain injury synergistically promote diverse …
B12/folate deficiency, depression, and traumatic brain injury synergistically promote diverse …
Interactions of oxidative stress and neurovascular inflammation in the pathogenesis of traumatic brain injury
PM Abdul-Muneer, N Chandra, J Haorah - Molecular neurobiology, 2015 - Springer
Traumatic brain injury (TBI) is a major cause of death in the young age group and leads to
persisting neurological impairment in many of its victims. It may result in permanent …
persisting neurological impairment in many of its victims. It may result in permanent …
Looking at the blood–brain barrier: molecular anatomy and possible investigation approaches
FL Cardoso, D Brites, MA Brito - Brain research reviews, 2010 - Elsevier
The blood–brain barrier (BBB) is a dynamic and complex interface between blood and the
central nervous system that strictly controls the exchanges between the blood and brain …
central nervous system that strictly controls the exchanges between the blood and brain …
Cellular mechanisms of IL‐17‐induced blood‐brain barrier disruption
J Huppert, D Closhen, A Croxford, R White… - The FASEB …, 2010 - Wiley Online Library
ABSTRACT Recently T‐helper 17 (Th17) cells were demonstrated to disrupt the blood‐brain
barrier (BBB) by the action of IL‐17A. The aim of the present study was to examine the …
barrier (BBB) by the action of IL‐17A. The aim of the present study was to examine the …
Brain endothelial cells and the glio-vascular complex
H Wolburg, S Noell, A Mack, K Wolburg-Buchholz… - Cell and tissue …, 2009 - Springer
We present and discuss the role of endothelial and astroglial cells in managing the blood-
brain barrier (BBB) and aspects of pathological alterations in the BBB. The impact of …
brain barrier (BBB) and aspects of pathological alterations in the BBB. The impact of …
Induction of oxidative and nitrosative damage leads to cerebrovascular inflammation in an animal model of mild traumatic brain injury induced by primary blast
PM Abdul-Muneer, H Schuetz, F Wang… - Free Radical Biology …, 2013 - Elsevier
We investigate the hypothesis that oxidative damage of the cerebral vascular barrier
interface (the blood–brain barrier, BBB) causes the development of mild traumatic brain …
interface (the blood–brain barrier, BBB) causes the development of mild traumatic brain …
Mechanism of alcohol-induced oxidative stress and neuronal injury
J Haorah, SH Ramirez, N Floreani, S Gorantla… - Free Radical Biology …, 2008 - Elsevier
Neuro-cognitive deficits, neuronal injury, and neurodegeneration are well documented in
alcoholics, yet the underlying mechanisms remain elusive. Oxidative damage of …
alcoholics, yet the underlying mechanisms remain elusive. Oxidative damage of …
Blood–brain barrier disruption and its involvement in neurodevelopmental and neurodegenerative disorders
The blood–brain barrier (BBB) is a highly specialized and dynamic compartment which
regulates the uptake of molecules and solutes from the blood. The relevance of the …
regulates the uptake of molecules and solutes from the blood. The relevance of the …