Primary and metastatic peritoneal surface malignancies
Peritoneal surface malignancies comprise a heterogeneous group of primary tumours,
including peritoneal mesothelioma, and peritoneal metastases of other tumours, including …
including peritoneal mesothelioma, and peritoneal metastases of other tumours, including …
mRNA vaccine era—mechanisms, drug platform and clinical prospection
S Xu, K Yang, R Li, L Zhang - International journal of molecular sciences, 2020 - mdpi.com
Messenger ribonucleic acid (mRNA)-based drugs, notably mRNA vaccines, have been
widely proven as a promising treatment strategy in immune therapeutics. The extraordinary …
widely proven as a promising treatment strategy in immune therapeutics. The extraordinary …
The effect of electrostatic high pressure nebulization on the stability, activity and ex vivo distribution of ionic self-assembled nanomedicines
H Braet, V Andretto, R Mariën, B Yücesan… - Acta Biomaterialia, 2023 - Elsevier
Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is applied to treat unresectable
peritoneal metastasis (PM), an advanced, end-stage disease with a poor prognosis …
peritoneal metastasis (PM), an advanced, end-stage disease with a poor prognosis …
Overcoming drug resistance by taking advantage of physical principles: pressurized intraperitoneal aerosol chemotherapy (PIPAC)
G Nadiradze, P Horvath, Y Sautkin, R Archid… - Cancers, 2019 - mdpi.com
Theoretical considerations as well as comprehensive preclinical and clinical data suggest
that optimizing physical parameters of intraperitoneal drug delivery might help to circumvent …
that optimizing physical parameters of intraperitoneal drug delivery might help to circumvent …
Intraperitoneal aerosolized drug delivery: technology, recent developments, and future outlook
M Rahimi-Gorji, L Van de Sande, C Debbaut… - Advanced Drug Delivery …, 2020 - Elsevier
Current therapies for patients with peritoneal metastases (PM) are only moderately effective.
Recently, a novel locoregional treatment method for PM was introduced, consisting of a …
Recently, a novel locoregional treatment method for PM was introduced, consisting of a …
Synergy between intraperitoneal aerosolization (PIPAC) and cancer nanomedicine: cisplatin-loaded polyarginine-hyaluronic acid nanocarriers efficiently eradicate …
M Shariati, G Lollo, K Matha, B Descamps… - … applied materials & …, 2020 - ACS Publications
Intra-abdominal dissemination of peritoneal nodules, a condition known as peritoneal
carcinomatosis (PC), is typically diagnosed in ovarian cancer patients at the advanced …
carcinomatosis (PC), is typically diagnosed in ovarian cancer patients at the advanced …
Exploring high pressure nebulization of Pluronic F127 hydrogels for intraperitoneal drug delivery
H Braet, M Rahimi-Gorji, C Debbaut… - European Journal of …, 2021 - Elsevier
Peritoneal metastasis is an advanced cancer type which can be treated with pressurized
intraperitoneal aerosol chemotherapy (PIPAC). Here, chemotherapeutics are nebulized …
intraperitoneal aerosol chemotherapy (PIPAC). Here, chemotherapeutics are nebulized …
Electrostatic intraperitoneal aerosol delivery of nanoparticles: proof of concept and preclinical validation
L Van de Sande, M Rahimi‐Gorji… - Advanced …, 2020 - Wiley Online Library
There is an increasing interest in intraperitoneal delivery of chemotherapy as an aerosol in
patients with peritoneal metastasis. The currently used technology is hampered by …
patients with peritoneal metastasis. The currently used technology is hampered by …
Fluorescence‐based quantification of messenger RNA and plasmid DNA decay kinetics in extracellular biological fluids and cell extracts
Extracellular and intracellular degradation of nucleic acids remains an issue in non‐viral
gene therapy. Understanding biodegradation is critical for the rational design of gene …
gene therapy. Understanding biodegradation is critical for the rational design of gene …
Fluorescence Correlation Spectroscopy to find the critical balance between extracellular association and intracellular dissociation of mRNA complexes
Abstract Fluorescence Correlation Spectroscopy (FCS) is a promising tool to study
interactions on a single molecule level. The diffusion of fluorescent molecules in and out of …
interactions on a single molecule level. The diffusion of fluorescent molecules in and out of …