Peptides with broad-spectrum antimicrobial activity are found widely expressed throughout
nature. As they participate in a number of different aspects of innate immunity in mammals …

The search for efficient antimicrobial therapies that can alleviate suffering caused by
infections from resistant bacteria is more urgent than ever before. Infections caused by multi …

Definition Antifungal drugs prevent topical or invasive fungal infections (mycoses) either by
stopping growth of fungi (termed fungistatic) or by killing the fungal cells (termed fungicidal) …

Respiratory infections are a major clinical problem, and treatment is increasingly
complicated by the emergence of microbial antibiotic resistance. Development of new …

Candida is an opportunistic fungal pathogen that colonizes the mucosal tract of humans.
Pathogenic infection occurs in the presence of conditions causing perturbations to the …

Abnormally high brain iron, resulting from the disrupted expression or function of proteins
involved in iron metabolism in the brain, is an initial cause of neuronal death in …

Oral epithelial cells (OECs) represent the first line of defense against viruses that are spread
via saliva, including Kaposi's sarcoma-associated herpesvirus (KSHV). Infection of humans …

New infection treatments are urgently needed to combat the rising threat of multi-drug
resistant bacteria. Despite early clinical set-backs attention has re-focused on host defense …

The oral cavity is a major entry point for bacteria and other microorganisms. Oral biofilms are
formed by mixed communities of microorganisms embedded in an exopolysaccharide …

The increasing frequency of multi-drug resistant microorganisms has driven research into
alternative therapeutic strategies. In this respect, natural antimicrobial peptides (AMPs) hold …