This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …

The ribosome is a multi-unit complex that translates mRNA into protein. Ribosome
biogenesis is the process that generates ribosomes and plays an essential role in cell …

Cardiometabolic diseases (CMDs) are currently the leading cause of death and disability
worldwide, and their underlying regulatory mechanisms remain largely unknown. N6 …

ABSTRACT Introduction N6-Methyladenosine (m6A), the most common and reversible
mRNA modification, has attracted considerable attention recently, and accumulating …

Background Cardiac fibrosis is a leading cause of cardiac dysfunction in patients with
diabetes. However, the underlying mechanisms of cardiac fibrosis remain unclear. This …

Atherosclerosis (AS) is a life-threatening vascular disease. RNA N6-methyladenosine (m6A)
modification level is dysregulated in multiple pathophysiologic processes including AS. In …

More than one hundred RNA modifications decorate the chemical and topological properties
of these ribose nucleotides, thereby executing their biological functions through post …

Abstract N6-methyladenosine (m 6 A) is one of the most prevalent internal transcriptional
modifications. Evidence has highlighted changes in m 6 A in metabolic disorders and …

Cardiovascular diseases lead the mortality and morbidity disease metrics worldwide. A
multitude of chemical base modifications in ribonucleic acids (RNAs) have been linked with …

Purpose Atherosclerosis (AS) is a primary cause of cardiovascular diseases. This study
investigated the mechanism of methyltransferase-like 3 (METTL3) in AS plaques via …