On iron metabolism and its regulation

ACS Vogt, T Arsiwala, M Mohsen, M Vogel… - International journal of …, 2021 - mdpi.com
Iron is a critical metal for several vital biological processes. Most of the body's iron is bound
to hemoglobin in erythrocytes. Iron from senescent red blood cells is recycled by …

Immunoporosis: role of innate immune cells in osteoporosis

Y Saxena, S Routh, A Mukhopadhaya - Frontiers in immunology, 2021 - frontiersin.org
Osteoporosis or porous bone disorder is the result of an imbalance in an otherwise highly
balanced physiological process known as 'bone remodeling'. The immune system is …

Regulation of immune function by polyphenols

S Ding, H Jiang, J Fang - Journal of immunology research, 2018 - Wiley Online Library
Immune dysfunction is caused by various factors, including changes in relevant immune
regulators and environmental stress. Immune system imbalance leads to a variety of …

Immune function and diversity of osteoclasts in normal and pathological conditions

MB Madel, L Ibáñez, A Wakkach, TJ De Vries… - Frontiers in …, 2019 - frontiersin.org
Osteoclasts (OCLs) are key players in controlling bone remodeling. Modifications in their
differentiation or bone resorbing activity are associated with a number of pathologies …

Recent advances on the anti-inflammatory and antioxidant properties of red grape polyphenols: in vitro and in vivo studies

T Magrone, M Magrone, MA Russo, E Jirillo - Antioxidants, 2019 - mdpi.com
In this review, special emphasis will be placed on red grape polyphenols for their antioxidant
and anti-inflammatory activities. Therefore, their capacity to inhibit major pathways …

Targeting systemic innate immune cells as a therapeutic avenue for Alzheimer disease

V Pons, S Rivest, R Dantzer - Pharmacological Reviews, 2022 - Elsevier
Alzheimer disease (AD) is the first progressive neurodegenerative disease worldwide, and
the disease is characterized by an accumulation of amyloid in the brain and …

Integrated bioinformatic analysis of the shared molecular mechanisms between osteoporosis and atherosclerosis

L Mo, C Ma, Z Wang, J Li, W He, W Niu… - Frontiers in …, 2022 - frontiersin.org
Background Osteoporosis and atherosclerosis are common in the elderly population,
conferring a heavy worldwide burden. Evidence links osteoporosis and atherosclerosis but …

Macrophage and nerve interaction in endometriosis

J Wu, H Xie, S Yao, Y Liang - Journal of neuroinflammation, 2017 - Springer
Dysregulation of the immune system in endometriotic milieus has been considered to play a
pivotal role in the pathogenesis of endometriosis. Macrophage recruitment and nerve fiber …

The MHC class II antigen presentation pathway in human monocytes differs by subset and is regulated by cytokines

J Lee, H Tam, L Adler, A Ilstad-Minnihan, C Macaubas… - PloS one, 2017 - journals.plos.org
Monocytes play a critical role in the innate and adaptive immune systems, performing
phagocytosis, presenting antigen, and producing cytokines. They are a heterogeneous …

[HTML][HTML] Remodeling of the osteoimmune microenvironment after biomaterials implantation in murine tibia: Single-cell transcriptome analysis

J Li, C Zhao, Y Xu, L Song, Y Chen, Y Xu, Y Ma… - Bioactive materials, 2023 - Elsevier
Osseointegration seems to be a foreign body reaction equilibrium due to the complicated
interactions between the immune and skeletal systems. The heterogeneity of the …