Oncological diseases have currently reached an epidemic scale, especially in industrialized
countries. Such a situation has prompted complex studies in medicinal chemistry focused on …

Thiazolidin-4-ones is an important heterocyclic ring system of a pharmacophore and a
privileged scaffold in medicinal chemistry. This review is focused on the latest scientific …

Thiazolidinedione (TZD) is one of the privileged heterocyclic rings and has shown many
biological applications in medicinal chemistry and drug discovery. This review covers the …

The 4‐thiazolidinone moiety is a privileged scaffold showing diversity in biological
responses like antiinflammatory, antidiabetic, anticancer, antitubercular, anesthetic …

Diclofenac (DCF) is well-known non-steroidal anti-inflammatory drug used in the treatment
of several cancer cell lines. DCF is derived from phenylacetic acid, and its pharmaceutical …

Novel pyrazoles incorporating coumarin moiety have been synthesized by the 1, 3-dipolar
cycloaddition reaction of the nitrilimines that were generated in situ from hydrazonyl halides …

Background: Cancer can be considered as a genetic as well as a metabolic disorder. The
current cancer treatment scenario looks like aggravating tumor cell metabolism, causing the …

Inflammation is critical to the formation and development of tumors and is closely associated
with cancer. Therefore, addressing inflammation and the mediators that contribute to the …

Due to the biological importance of diclofenac derivatives which are included in the
composition of the active substance in many medicines used in the treatment of infections …

Abstract A series of novel 2, 3, 5‐trisubstituted thiazolidinone derivatives was designed and
synthesized. Compounds were tested for their antimicrobial and antitubercular activities …