Non melanoma skin cancer pathogenesis overview
(1) Background: Non-melanoma skin cancer is the most frequently diagnosed cancer in
humans. The process of skin carcinogenesis is still not fully understood. However, several …
humans. The process of skin carcinogenesis is still not fully understood. However, several …
The role of DLLs in cancer: a novel therapeutic target
MX Xiu, YM Liu, B Kuang - OncoTargets and therapy, 2020 - Taylor & Francis
Delta-like ligands (DLLs) control Notch signaling. DLL1, DLL3 and DLL4 are frequently
deregulated in cancer and influence tumor growth, the tumor vasculature and tumor …
deregulated in cancer and influence tumor growth, the tumor vasculature and tumor …
Prognostic effect of VEGF gene variants in metastatic non-small-cell lung cancer patients
Introduction Clinical and pathological characteristics are still considered prognostic markers
in metastatic non-small-cell lung cancer (NSCLC) patients but they cannot explain all …
in metastatic non-small-cell lung cancer (NSCLC) patients but they cannot explain all …
Genetic polymorphisms of vascular endothelial growth factor (VEGF) associated with gastric cancer recurrence after curative resection with adjuvant chemotherapy
YJ Kim, WC Chung, KH Jun, HM Chin - BMC cancer, 2019 - Springer
Background The relationship between polymorphisms in vascular endothelial growth factor
(VEGF) and gastric cancer is still inconclusive. We investigated whether there is an …
(VEGF) and gastric cancer is still inconclusive. We investigated whether there is an …
Retinoblastoma binding protein 2 (RBP2) promotes HIF-1α–VEGF-induced angiogenesis of non-small cell lung cancer via the AKT pathway
L Qi, F Zhu, S Li, L Si, L Hu, H Tian - PloS one, 2014 - journals.plos.org
Background Pathological angiogenesis plays an essential role in tumor aggressiveness and
leads to unfavorable prognosis. The aim of this study is to detect the potential role of …
leads to unfavorable prognosis. The aim of this study is to detect the potential role of …
Transcriptional regulation of the VEGF gene in dependence of individual genomic variations
CS Metzger, D Koutsimpelas, J Brieger - Cytokine, 2015 - Elsevier
Overexpression of the vascular endothelial growth factor (VEGF) gene has been associated
with advanced stage and poor survival in several cancers. The majority of disease …
with advanced stage and poor survival in several cancers. The majority of disease …
CXC chemokine ligand 4 (CXCL4) is predictor of tumour angiogenic activity and prognostic biomarker in non-small cell lung cancer (NSCLC) patients undergoing …
A Spaks, D Svirina, I Spaka, I Jaunalksne, D Breiva… - Biomarkers, 2016 - Taylor & Francis
Objective: To evaluate the association of CXC chemokine ligand 4 (CXCL4) plasma levels
with tumour angiogenesis in non-small cell lung cancer (NSCLC) and to assess association …
with tumour angiogenesis in non-small cell lung cancer (NSCLC) and to assess association …
[HTML][HTML] Single nucleotide polymorphisms in VEGF gene are associated with an increased risk of osteosarcoma
Z Tie, R Bai, Z Zhai, G Zhang, H Zhang… - … journal of clinical and …, 2014 - ncbi.nlm.nih.gov
We aimed to assess whether the five common SNPs can affect the risk of osteosarcoma, and
its association with demographic characteristics of osteosarcoma. 165 osteosarcoma …
its association with demographic characteristics of osteosarcoma. 165 osteosarcoma …
Impact of VEGF Gene Polymorphisms in Elderly Cancer Patients: Clinical Outcome and Toxicity
D Della-Morte, S Riondino, P Ferroni… - …, 2015 - Taylor & Francis
Vascular endothelial growth factors (VEGFs) are the key regulators in angiogenesis and
have been shown to play a significant role in the progression and prognosis of angiogenesis …
have been shown to play a significant role in the progression and prognosis of angiogenesis …
Hedgehog/Gli1 signal pathway facilitates proliferation, invasion, and migration of cutaneous SCC through regulating VEGF
Q Sun, J Bai, R Lv - Tumor Biology, 2016 - Springer
Abstract Since hedgehog (HH)/Gli1 that contributes to cancer proliferation and metastasis
has been masked for decades, the signaling pathway was investigated about its exact role …
has been masked for decades, the signaling pathway was investigated about its exact role …