[HTML][HTML] Loop competition and extrusion model predicts CTCF interaction specificity

W Xi, MA Beer - Nature communications, 2021 - nature.com
Three-dimensional chromatin looping interactions play an important role in constraining
enhancer–promoter interactions and mediating transcriptional gene regulation. CTCF is …

Nuclear organization in cutaneous anaplastic large cell lymphomas

S Mai, K Gough, E Eftekharpour, T Klonisch - 2022 - mspace.lib.umanitoba.ca
Genomes of eukaryotic cells are organized in 3D non-random multiscale structures that
have significant effects on function of their genome, of the cell and collectively with other …

Disruption of chromosome territories in Multiple Myeloma

M Fabião de Lima - 2022 - mspace.lib.umanitoba.ca
Background: Multiple Myeloma (MM) is an oligoclonal cancer of plasma cells. Currently, MM
is an incurable disease. MM displays altered gene expression, chromosome aberrations …

[PDF][PDF] Statics and dynamics of physical linking: from confined polymers to chromatin filaments

G Amici - 2020 - iris.sissa.it
During last decades, the improvement of nanotechnologies led to the possibility of
performing experiments at a single molecule level in a variety of conditions. This allowed us …