Non-coding RNAs in human health and disease: potential function as biomarkers and therapeutic targets

T Loganathan, GP Doss C - Functional & integrative genomics, 2023 - Springer
Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …

[PDF][PDF] A simple guide to de novo transcriptome assembly and annotation

V Raghavan, L Kraft, F Mesny… - Briefings in …, 2022 - academic.oup.com
A transcriptome constructed from short-read RNA sequencing (RNA-seq) is an easily
attainable proxy catalog of protein-coding genes when genome assembly is unnecessary …

Linking discoveries, mechanisms, and technologies to develop a clearer perspective on plant long noncoding RNAs

K Palos, L Yu, CE Railey, AC Nelson Dittrich… - The Plant …, 2023 - academic.oup.com
Long noncoding RNAs (lncRNAs) are a large and diverse class of genes in eukaryotic
genomes that contribute to a variety of regulatory processes. Functionally characterized …

Long non-coding RNA in plants in the era of reference sequences

H Budak, SB Kaya, HB Cagirici - Frontiers in Plant Science, 2020 - frontiersin.org
The discovery of non-coding RNAs (ncRNAs), and the subsequent elucidation of their
functional roles, was largely delayed due to the misidentification of non-protein-coding parts …

[HTML][HTML] Next-generation biology: sequencing and data analysis approaches for non-model organisms

RR da Fonseca, A Albrechtsen, GE Themudo… - Marine genomics, 2016 - Elsevier
As sequencing technologies become more affordable, it is now realistic to propose studying
the evolutionary history of virtually any organism on a genomic scale. However, when …

EnTAP: Bringing faster and smarter functional annotation to non‐model eukaryotic transcriptomes

AJ Hart, S Ginzburg, M Xu, CR Fisher… - Molecular ecology …, 2020 - Wiley Online Library
Abstract EnTAP (Eukaryotic Non‐Model Transcriptome Annotation Pipeline) was designed
to improve the accuracy, speed, and flexibility of functional gene annotation for de novo …

Interactions among lncRNAs, miRNAs and mRNA in colorectal cancer

XJ Tang, W Wang, SS Hann - Biochimie, 2019 - Elsevier
Long non-coding RNAs (lncRNAs) are longer than 200 nts non-coding transcripts and have
recently emerged as one of the largest and significantly diverse RNA families whereas …

Finding a partner in the ocean: molecular and evolutionary bases of the response to sexual cues in a planktonic diatom

S Basu, S Patil, D Mapleson, MT Russo… - New …, 2017 - Wiley Online Library
Microalgae play a major role as primary producers in aquatic ecosystems. Cell signalling
regulates their interactions with the environment and other organisms, yet this process in …

Identification of circular RNAs in kiwifruit and their species-specific response to bacterial canker pathogen invasion

Z Wang, Y Liu, D Li, L Li, Q Zhang, S Wang… - Frontiers in plant …, 2017 - frontiersin.org
Research studies have recently focused on circle RNAs (circRNAs) in relation to their
regulatory functions in animals. However, the systematic identification of circRNAs in plants …

A long noncoding RNA regulates inflammation resolution by mouse macrophages through fatty acid oxidation activation

Y Nakayama, K Fujiu, R Yuki, Y Oishi… - Proceedings of the …, 2020 - National Acad Sciences
Proper resolution of inflammation is vital for repair and restoration of homeostasis after
tissue damage, and its dysregulation underlies various noncommunicable diseases, such as …