Targeting circular RNAs as a therapeutic approach: current strategies and challenges
Significant progress has been made in circular RNA (circRNA) research in recent years.
Increasing evidence suggests that circRNAs play important roles in many cellular processes …
Increasing evidence suggests that circRNAs play important roles in many cellular processes …
The bioinformatics toolbox for circRNA discovery and analysis
Circular RNAs (circRNAs) are a unique class of RNA molecule identified more than 40 years
ago which are produced by a covalent linkage via back-splicing of linear RNA. Recent …
ago which are produced by a covalent linkage via back-splicing of linear RNA. Recent …
Biogenesis, functions and clinical significance of circRNAs in gastric cancer
C Shan, Y Zhang, X Hao, J Gao, X Chen, K Wang - Molecular cancer, 2019 - Springer
Gastric cancer (GC) is one of the most common malignant tumours in the world and has high
morbidity and mortality. Circular RNAs (circRNAs) are a class of non-coding RNAs with …
morbidity and mortality. Circular RNAs (circRNAs) are a class of non-coding RNAs with …
Circular RNA s in hepatocellular carcinoma: functions and implications
L Fu, Z Jiang, T Li, Y Hu, J Guo - Cancer Medicine, 2018 - Wiley Online Library
At present, as hotspot members of the noncoding RNA network, circular RNA s (circ RNA s)
with distinct properties and diverse pathophysiological functions are being increasingly …
with distinct properties and diverse pathophysiological functions are being increasingly …
Circular RNA circSVIL Promotes Myoblast Proliferation and Differentiation by Sponging miR-203 in Chicken
H Ouyang, X Chen, W Li, Z Li, Q Nie, X Zhang - Frontiers in genetics, 2018 - frontiersin.org
Circular RNAs (circRNAs), expressed abundantly and universally in various eukaryotes, are
involved in growth and development of animals. Our previous study on circRNA sequencing …
involved in growth and development of animals. Our previous study on circRNA sequencing …
Circular RNA profiling identifies novel circPPARA that promotes intramuscular fat deposition in pigs
B Li, Y He, W Wu, X Tan, Z Wang… - Journal of Agricultural …, 2022 - ACS Publications
Intramuscular fat (IMF) content plays an important role in pork quality. Circular RNAs
(circRNAs) implicate various biological processes; however, the regulatory mechanisms and …
(circRNAs) implicate various biological processes; however, the regulatory mechanisms and …
Circular RNA circHIPK3 promotes the proliferation and differentiation of chicken myoblast cells by sponging miR-30a-3p
B Chen, J Yu, L Guo, MS Byers, Z Wang, X Chen, H Xu… - Cells, 2019 - mdpi.com
Circular RNAs and microRNAs widely exist in various species and play crucial roles in
multiple biological processes. It is essential to study their roles in myogenesis. In our …
multiple biological processes. It is essential to study their roles in myogenesis. In our …
circRNAome profiling reveals circFgfr2 regulates myogenesis and muscle regeneration via a feedback loop
Abstract Background Circular RNAs (circRNAs) represent a novel class of non‐coding RNAs
formed by a covalently closed loop and play crucial roles in many biological processes …
formed by a covalently closed loop and play crucial roles in many biological processes …
Circular RNA regulation of myogenesis
P Zhang, Z Chao, R Zhang, R Ding, Y Wang, W Wu… - Cells, 2019 - mdpi.com
Circular RNA (circRNA) is a novel class of non-coding RNA generated by pre-mRNA back
splicing, which is characterized by a closed-loop structure. Although circRNAs were firstly …
splicing, which is characterized by a closed-loop structure. Although circRNAs were firstly …
MyoD-induced circular RNA CDR1as promotes myogenic differentiation of skeletal muscle satellite cells
L Li, Y Chen, L Nie, X Ding, X Zhang, W Zhao… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Many protein coding and non-coding genes interplay in governing skeletal muscle
formation. Nevertheless, comparing with the linear transcripts, functions of covalently closed …
formation. Nevertheless, comparing with the linear transcripts, functions of covalently closed …