Cancer stem cells (CSCs) are the main culprits involved in therapy resistance and disease
recurrence in colorectal carcinoma (CRC). Results using cell culture, animal models and …

Glioblastoma (GBM) is known as a tumor type, which arises from astrocytes. Several studies
indicated that GBM tumor cells are malignant. This is because of the fact that they consist of …

Oxaliplatin (OXA), is a third generation platinum drug used as first‐line chemotherapy in
colorectal cancer (CRC). Cancer cells acquires resistance to anti‐cancer drug and develops …

Despite recent progresses in tumor therapy and increased knowledge in tumor biology,
tumor remains a common and lethal disease worldwide. Cancer stem cells (CSCs) are a …

The adenosine triphosphate (ATP)-binding cassette efflux transporter G2 (ABCG2) was
originally discovered in a multidrug-resistant breast cancer cell line. Studies in the past have …

MicroRNAs (miRNAs) are small single-stranded RNAs that repress mRNA translation and
trigger mRNA degradation. Of the∼ 1900 miRNA-encoding genes present in the human …

Cancer stem cells (CSCs) are a small group of cancer cells, which contribute to
tumorigenesis and cancer progression. Cancer cells undergoing epithelial-to-mesenchymal …

Colorectal cancer (CRC), a multifactorial disease, is usually induced and developed through
complex mechanisms, including impact of diet and lifestyle, genomic abnormalities, change …

Background Given the differences in embryonic origin, vascular and nervous supplies,
microbiotic burden, and main physiological functions of left and right colons, tumor location …

Membrane-type matrix metalloproteases (MT-MMP) are pivotal regulators of cell invasion,
growth and survival. Tethered to the cell membranes by a transmembrane domain or GPI …