Cryptococcus neoformans and Cryptococcus gattii species complexes cause
meningoencephalitis with high fatality rates and considerable morbidity, particularly in …

Type I IFNs are so‐named because they interfere with viral infection in vertebrate cells. The
study of cellular responses to type I IFNs led to the discovery of the JAK‐STAT signaling …

The first STAT family member, STAT1, is an essential component of interferon (IFN)-
signaling, which mediates several cellular functions in response to stimulation by cytokines …

Significance: Macrophages are crucial for tissue homeostasis. Based on their activation,
they might display classical/M1 or alternative/M2 phenotypes. M1 macrophages produce pro …

Despite the international scientific community's commitment to improve clinical knowledge
about coronavirus disease 2019 (COVID‐19), knowledge regarding molecular details …

A central feature of diabetic (Db) wounds is the persistence of chronic inflammation, which is
partly due to the prolonged presence of proinflammatory (M1) macrophages. Using in vivo …

The vast majority of infection with cryptococcal species occurs with Cryptococcus
neoformans in the severely immunocompromised. A significant exception to this is the …

Cryptococcus neoformans and C. gattii are fungal pathogens that cause life-threatening
disease. These fungi commonly enter their host via inhalation into the lungs where they …

Cryptococcus species, the etiological agents of cryptococcosis, are encapsulated fungal
yeasts that predominantly cause disease in immunocompromised individuals, and are …

Cryptococcus neoformans, the predominant etiological agent of cryptococcosis, is an
opportunistic fungal pathogen that primarily affects AIDS patients and patients undergoing …