[HTML][HTML] Alzheimer's disease pathophysiology in the retina

BP Gaire, Y Koronyo, DT Fuchs, H Shi… - Progress in Retinal and …, 2024 - Elsevier
The retina is an emerging CNS target for potential noninvasive diagnosis and tracking of
Alzheimer's disease (AD). Studies have identified the pathological hallmarks of AD …

Optical coherence tomography in patients with Alzheimer's disease: what can it tell us?

A Song, N Johnson, A Ayala, AC Thompson - Eye and brain, 2021 - Taylor & Francis
Purpose Although Alzheimer's disease (AD) is a leading cause of dementia worldwide, its
clinical diagnosis remains a challenge. Optical coherence tomography (OCT) and OCT with …

[HTML][HTML] Comparison of retinal microvasculature in patients with Alzheimer's disease and primary open-angle glaucoma by optical coherence tomography …

P Zabel, JJ Kaluzny… - … & Visual Science, 2019 - tvst.arvojournals.org
Purpose: Comparison of retinal microvasculature within the macula and the optic nerve
head in the eyes of patients with Alzheimer's disease (AD), primary open-angle glaucoma …

Decreased retinal vascular density in Alzheimer's disease (AD) and mild cognitive impairment (MCI): an optical coherence tomography angiography (OCTA) study

X Wang, Q Zhao, R Tao, H Lu, Z Xiao… - Frontiers in Aging …, 2021 - frontiersin.org
Background To explore the retinal vascular density changes in Alzheimer's disease (AD)
and mild cognitive impairment (MCI) patients using optical coherence tomography …

Reflections on the utility of the retina as a biomarker for Alzheimer's disease: a literature review

J Ngolab, P Honma, RA Rissman - Neurology and therapy, 2019 - Springer
As a part of the central nervous system, the retina may reflect both physiologic processes
and abnormalities related to diseases of the brain. Indeed, a concerted effort has been put …

Ophthalmic biomarkers for Alzheimer's disease: a review

A Majeed, B Marwick, H Yu, H Fadavi… - Frontiers in Aging …, 2021 - frontiersin.org
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
neuronal loss, extracellular amyloid-β (Aβ) plaques, and intracellular neurofibrillary tau …

Retinal imaging biomarkers of Alzheimer's disease: A systematic review and meta‐analysis of studies using brain amyloid beta status for case definition

G Ashraf, M McGuinness, MA Khan… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction We performed a systematic review and meta‐analysis of the association
between retinal imaging parameters and Alzheimer's disease (AD). Methods PubMed …

[HTML][HTML] Ganglion cell layer thinning in prodromal Alzheimer's disease defined by amyloid PET

A López-de-Eguileta, C Lage, S López-García… - Alzheimer's & Dementia …, 2019 - Elsevier
Introduction The objective of this study was to investigate and compare optic nerve and
retinal layers in eyes of patients with mild cognitive impairment (MCI) and Alzheimer's …

Huntington's disease and neurovascular structure of retina

E Amini, M Moghaddasi, SAH Habibi, Z Azad… - Neurological …, 2022 - Springer
Background Retinal biomarkers in neurodegenerative disorders have attracted much
attention in recent years. Recent studies have reported visual dysfunction in Huntington's …

Afferent and efferent visual markers of Alzheimer's disease: A review and update in early stage disease

SZ Wu, AV Masurkar, LJ Balcer - Frontiers in Aging Neuroscience, 2020 - frontiersin.org
Vision, which requires extensive neural involvement, is often impaired in Alzheimer's
disease (AD). Over the last few decades, accumulating evidence has shown that various …