Since the discovery of chlorpromazine (CPZ) in 1952, first-generation antipsychotics (FGAs)
have revolutionized psychiatric care in terms of facilitating discharge from hospital and …

Family study results are consistent with genetic effects making substantial contributions to
risk of psychiatric disorders such as schizophrenia, yet robust identification of specific …

Importance Although adults with schizophrenia have a significantly increased risk of
premature mortality, sample size limitations of previous research have hindered the …

People with severe mental illness have a considerably shorter lifespan than the general
population. This excess mortality is mainly due to physical illness. Next to mental illness …

Importance Bipolar disorder is associated with premature mortality, but the specific causes
and underlying pathways are unclear. Objective To examine the physical health effects of …

Objective Schizophrenia is associated with premature mortality, but the specific causes and
pathways are unclear. The authors used outpatient and inpatient data for a national …

The high societal and individual cost of schizophrenia necessitates finding better, more
effective treatment, diagnosis, and prevention strategies. One of the obstacles in this …

Even though individuals with psychiatric conditions have a prevalence of smoking
approximately 2–4 times greater than the general population, surprisingly little evidence …

Background: There is a lack of scientific consensus about cancer comorbidity in people with
central nervous system (CNS) disorders. This study assesses the co-occurrence of cancers …

BackgroundThere is a higher mortality rate due to cancer in people with mental illness and
previous work suggests suboptimal medical care in this population. It remains unclear if this …