Radiation is a significant treatment for patients with head and neck cancer. Despite
advances to improve treatment, many tumors acquire radiation resistance resulting in poor …

Tumors are known to be heterogeneous containing a dynamic mixture of phenotypically and
functionally different tumor cells. The two concepts attempting to explain the origin of …

Ataxia-telangiectasia mutated (ATM) is needed for the initiation of the double-strand break
(DSB) repair by homologous recombination (HR). ATM triggers DSB end resection by …

Gastric cancer (GC) is the fourth most common cancer and the third leading cause of cancer
mortality worldwide. MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) are the …

Radiotherapy is a cancer treatment that applies high doses of ionizing radiation to induce
cell death, mainly by triggering DNA double-strand breaks. The outcome of radiotherapy …

Background: Ataxia telangiectasia mutated (ATM) is a kinase that has a central role in the
maintenance of genomic integrity by activating cell cycle checkpoints and promoting repair …

Cervical carcinoma (CC) is one of the most common cancers and a leading cause of
mortality in women worldwide. Epidemiologic and experimental data have clearly …

Circular RNAs (circRNAs) are a new class of noncoding RNAs, play a crucial role in tumor
initiation and development. Hsa_circ_0001546 is a novel circular RNA that was …

Radiotherapy is one of the most important treatment options for localized early-stage or
advanced-stage prostate cancer (CaP). Radioresistance (relapse after radiotherapy) is a …

SUMMARY A recent reduction in the number of smoke-related tumours has been observed
thanks to the diffusion of anti-tobacco campaigns carried out in the majority of developed …