Maternally expressed gene 3 (MEG3) is an imprinted gene belonging to the imprinted DLK1–
MEG3 locus located at chromosome 14q32. 3 in humans. Its mouse ortholog, Meg3, also …

Abstract Maternally expressed gene 3 (MEG3) is a long non-coding RNA (lncRNA) located
on chromosome 14q32. 3. Direct sequencing experiments have shown monoallelic …

From transcriptional noise to dark matter of biology, the rapidly changing view of long non-
coding RNA (lncRNA) leads to deep understanding of human complex diseases induced by …

Substantial advances have been made recently in the pathobiology of pituitary tumors.
Similar to many other endocrine tumors, over the last few years we have recognized the role …

LncRNAs are emerging as integral functional and regulatory components of normal
biological activities and are now considered as critically involved in the development of …

Human pituitary adenomas are the most common intracranial neoplasms. Approximately 5%
of them are familial adenomas. Patients with familial tumors carry germline mutations in …

The human genome encodes tens of thousands of long non-coding RNAs (lncRNAs), a
novel and important class of genes. Our knowledge of lncRNAs has grown exponentially …

Pituitary tumours, the most frequent intracranial tumour, are historically considered benign.
However, various pieces of clinical evidence and recent advances in pathological and …

Pituitary adenomas are common tumors of the adenohypophysis which can cause
considerable morbidity, due to excessive hormonal secretion or compression and local …

Human clinically non-functioning pituitary adenomas (NFAs) account for approximately 40%
of diagnosed pituitary tumors. Epigenetic mutations in tumor suppressive genes play an …