Therapeutic uses of selected pyrimidine compounds with anti-Mer tyrosine kinase activity

X Wang, W Zhang, S Frye - US Patent 9,649,309, 2017 - Google Patents
2015-05-12 Assigned to THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
reassignment THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL ASSIGNMENT …

Therapeutic uses of selected pyrrolopyrimidine compounds with anti-mer tyrosine kinase activity

X Wang, W Zhang, S Frye - US Patent 10,004,755, 2018 - Google Patents
2017-02-08 Assigned to THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
reassignment THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL ASSIGNMENT …

Inhalable imatinib formulations, manufacture, and uses thereof

B Dake, R Niven - US Patent 11,464,776, 2022 - Google Patents
BACKGROUND Pulmonary arterial hypertension (PAH) is a condition involving elevated
blood pressure in the arteries of the lungs with unknown causes and is differentiated from …

Pyrimidine compounds for the treatment of cancer

X Wang, W Zhang, D Kireev, D Zhang… - US Patent …, 2017 - Google Patents
Described are compounds of Formula I or Formula II: wherein: ring A is a 5-or 6-membered
heteroaryl group; OO dashed lines are optional double bonds; X is N or O: Y is a Related US …

MerTK-specific pyrazolopyrimidine compounds

X Wang, S Frye - US Patent 9,603,850, 2017 - Google Patents
Related US Application Data (60) Provisional application No. 61/978.268, filed on Apr. 11,
2014, provisional application No. 61/978,281, filed on Apr. 11, 2014, provisional application …

Inhalable imatinib formulations, manufacture, and uses thereof

B Dake, R Niven, AD Levin - US Patent 11,229,650, 2022 - Google Patents
7,638,627 B2 7,674,901 B2 9,925,184 B2 2006/0223817 Al 2006/0275372 A1
2008/0103305 Al 2008/0181958 Al 2008/0207904 A1 2009/0136579 A1 2010/0330130 A1 …

Use of kinase inhibitors to manage tuberculosis and other infectious diseases

D Kalman - US Patent 10,537,574, 2020 - Google Patents
This disclosure relates to the use of kinase inhibitor to treat or prevent infectious diseases
such as tuberculosis. In certain embodiments, this disclosure relates to treating or prevent …

Inhalable imatinib formulations, manufacture, and uses thereof

B Dake, R Niven - US Patent 11,413,289, 2022 - Google Patents
BACKGROUND Pulmonary arterial hypertension (PAH) is a condition involving elevated
blood pressure in the arteries of the lungs with unknown causes and is differentiated from …

Therapeutic uses of selected pyrrolopyrimidine compounds with anti-mer tyrosine kinase activity

X Wang, W Zhang, S Frye - US Patent 9,555,031, 2017 - Google Patents
2015-05-12 Assigned to THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
reassignment THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL ASSIGNMENT …

Therapeutic uses of selected pyrazolopyrimidine compounds with anti-Mer tyrosine kinase activity

X Wang, S Frye - US Patent 9,555,030, 2017 - Google Patents
2015-05-12 Assigned to THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
reassignment THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL ASSIGNMENT …