[HTML][HTML] Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification

MA La Merrill, LN Vandenberg, MT Smith… - Nature Reviews …, 2020 - nature.com
Endocrine-disrupting chemicals (EDCs) are exogenous chemicals that interfere with
hormone action, thereby increasing the risk of adverse health outcomes, including cancer …

Endocrine disrupting chemicals: exposure, effects on human health, mechanism of action, models for testing and strategies for prevention

B Yilmaz, H Terekeci, S Sandal… - Reviews in endocrine and …, 2020 - Springer
Abstract Endocrine Disrupting Chemicals (EDCs) are a global problem for environmental
and human health. They are defined as “an exogenous chemical, or mixture of chemicals …

[HTML][HTML] Emerging evidence that the mammalian sperm epigenome serves as a template for embryo development

A Lismer, S Kimmins - Nature communications, 2023 - nature.com
Although more studies are demonstrating that a father's environment can influence child
health and disease, the molecular mechanisms underlying non-genetic inheritance remain …

EDC-2: the Endocrine Society's second scientific statement on endocrine-disrupting chemicals

AC Gore, VA Chappell, SE Fenton, JA Flaws… - Endocrine …, 2015 - academic.oup.com
Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …

[HTML][HTML] Environmental chemicals and breast cancer: An updated review of epidemiological literature informed by biological mechanisms

KM Rodgers, JO Udesky, RA Rudel, JG Brody - Environmental research, 2018 - Elsevier
Background Many common environmental chemicals are mammary gland carcinogens in
animal studies, activate relevant hormonal pathways, or enhance mammary gland …

Human exposure to endocrine disrupting chemicals: effects on the male and female reproductive systems

S Sifakis, VP Androutsopoulos, AM Tsatsakis… - Environmental …, 2017 - Elsevier
Endocrine disrupting chemicals (EDCs) comprise a group of chemical compounds that have
been examined extensively due to the potential harmful effects in the health of human …

The impact of agricultural chemical inputs on environment: global evidence from informetrics analysis and visualization

L Zhang, C Yan, Q Guo, J Zhang… - International Journal of …, 2018 - academic.oup.com
This paper identifies and analyzes salient research frontiers, research hotspots and high-
frequency terms using aggregated and multiple-source literature records related to the topic …

Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor β

GGJM Kuiper, JG Lemmen, BO Carlsson… - …, 1998 - academic.oup.com
The rat, mouse and human estrogen receptor (ER) exists as two subtypes, ERα and ERβ,
which differ in the C-terminal ligand-binding domain and in the N-terminal transactivation …

Persistent organochlorinated pesticides and mechanisms of their toxicity

EJ Mrema, FM Rubino, G Brambilla, A Moretto… - Toxicology, 2013 - Elsevier
Persistent organic pollutants comprised of organic chemicals like polychlorinated biphenyls,
dibenzo-p-dioxins, dibenzofurans and organochlorinated pesticides which have many …

Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β

GGJM Kuiper, BO Carlsson, KAJ Grandien… - …, 1997 - academic.oup.com
The rat estrogen receptor (ER) exists as two subtypes, ERα and ERβ, which differ in the C-
terminal ligand binding domain and in the N-terminal transactivation domain. In this study …