Bioelectric signaling: Reprogrammable circuits underlying embryogenesis, regeneration, and cancer

M Levin - Cell, 2021 - cell.com
How are individual cell behaviors coordinated toward invariant large-scale anatomical
outcomes in development and regeneration despite unpredictable perturbations …

Bioelectric signaling as a unique regulator of development and regeneration

MP Harris - Development, 2021 - journals.biologists.com
It is well known that electrical signals are deeply associated with living entities. Much of our
understanding of excitable tissues is derived from studies of specialized cells of neurons or …

MAPK/ERK pathway as a central regulator in vertebrate organ regeneration

X Wen, L Jiao, H Tan - International journal of molecular sciences, 2022 - mdpi.com
Damage to organs by trauma, infection, diseases, congenital defects, aging, and other
injuries causes organ malfunction and is life-threatening under serious conditions. Some of …

The art of fin regeneration in zebrafish

C Pfefferli, A Jaźwińska - Regeneration, 2015 - Wiley Online Library
The zebrafish fin provides a valuable model to study the epimorphic type of regeneration,
whereby the amputated part of the appendage is nearly perfectly replaced. To accomplish …

Molecular bioelectricity: how endogenous voltage potentials control cell behavior and instruct pattern regulation in vivo

M Levin - Molecular biology of the cell, 2014 - Am Soc Cell Biol
In addition to biochemical gradients and transcriptional networks, cell behavior is regulated
by endogenous bioelectrical cues originating in the activity of ion channels and pumps …

[HTML][HTML] Hallmarks of regeneration

KD Poss, EM Tanaka - Cell stem cell, 2024 - cell.com
Regeneration is a heroic biological process that restores tissue architecture and function in
the face of day-to-day cell loss or the aftershock of injury. Capacities and mechanisms for …

Model systems for regeneration: planarians

M Ivankovic, R Haneckova, A Thommen… - …, 2019 - journals.biologists.com
Planarians are a group of flatworms. Some planarian species have remarkable regenerative
abilities, which involve abundant pluripotent adult stem cells. This makes these worms a …

Recent advancements in understanding fin regeneration in zebrafish

IM Sehring, G Weidinger - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
Zebrafish have the remarkable ability to fully regenerate a lost appendage, faithfully
restoring its size, shape and tissue patterning. Studies over the past decades have identified …

Signaling networks organizing regenerative growth of the zebrafish fin

D Wehner, G Weidinger - Trends in Genetics, 2015 - cell.com
In contrast to mammals, adult salamanders and fish can completely regenerate their
appendages after amputation. The cellular and molecular mechanisms underlying this …

[HTML][HTML] The genetic basis of morphological diversity in domesticated goldfish

T Kon, Y Omori, K Fukuta, H Wada, M Watanabe… - Current Biology, 2020 - cell.com
Although domesticated goldfish strains exhibit highly diversified phenotypes in morphology,
the genetic basis underlying these phenotypes is poorly understood. Here, based on …